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by Vincent Racaniello
A review of the infectious diseases literature from the previous two weeks.
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On episode #111 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/7 – 7/20/26. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Impact of HIV-1 RNA Assay Selection on Low-Level Viremia and Clinical Trial Endpoint Interpretations (CID) Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus Antibodies—United States, 2017–March 2020 (JID) Concordance between nasopharyngeal swab and bronchoalveolar lavage PCR for respiratory viruses (CMI: Clinical Microbiology and Infection) Influenza vaccine effectiveness against outpatient acute respiratory illness with laboratory-confirmed influenza, United States, 2024–25 season (CID) Bacterial Clinical Impact of the BIOFIRE FILMARRAY Pneumonia Panel in the Veterans Affairs Healthcare System: A Difference-in-Differences Study (CID) Routine serial follow-up blood cultures after a negative result within 48 hours of methicillin-susceptible Staphylococcus aureus bacteremia: low yield, high cost (CID) Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? (CID) Clinical Features of Clostridial Necrotizing Soft-Tissue Infections: Analysis of a Prospective Scandinavian Cohort Study(OFID) Fungal The Last of US Season 2 (YouTube) Molecular Epidemiology of Candidozyma auris Within a Case Cluster in North-Central Florida: Diverse Origins and Long-term Persistence ofStrain (OFID) Characteristics of Mortality in HIV-negative Cryptococcosis Patients: Analysis of a Cohort of 743 Patients (OFID) Parasitic Positive Strongyloides Serology: A Descriptive Analysis Across Geographically Distinct Academic Medical Centers (Transplant Infectious Diseases) Miscellaneous Community-acquired pneumonia: imperfect tests, imperfect clinicians or both? (CMI: Clinical Microbiology and Infection) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #110 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 6/23 – 7/6/26. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Oseltamivir Resistance in Human Influenza A(H5N1) and A(H7N9) Infections: a mini review (OFID) Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1 (OFID) Bacterial Impact of Multiplex PCR Blood-Culture Identification Panels on Clinical Outcomes, Antimicrobial Stewardship, and Economic Impact in US Hospitals: A Systematic Review and Meta-Analysis (OFID) Legionellosis Outbreaks Associated with Two Hotels — U.S. Virgin Islands, October 2024–April 2025 (CDC: MMWR) Impact of Methicillin Resistance on Outcomes of Staphylococcus aureus Bacteremia at a U.S. Center, 2023–2024 (OFID) Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections (JAMA:Open Network) Fungal The Last of US Season 2 (YouTube) Comparing rapid molecular and culture methods for detecting fungal contamination in healthcare environments (Infection Control and Hospital Epidemiology) Surveillance for Candida auris — United States, 2022–2024 (CDC: MMWR) Parasitic Alpha-gal Immunoglobulin E Seroprevalence Among Blood Donors — 10 States, 2024–2025 (CDC: MMWR) Schistosomiasis vaccine SchistoShield induces functional immune memory responses in US and African populations (njp: Vaccines) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #109 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/4 – 6/22/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral CMV viraemia is associated with mortality among children with HIV starting antiretroviral therapy in sub-Saharan Africa (CID) Bacterial Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia(NEJM) A fatal case of Legionella micdadei prosthetic valve endocarditis diagnosed by plasma microbial cell-free DNA metagenomic sequencing (LANCET: Infectious Diseases) Legionnaires Disease Associated with a Private-Use Hot Tub in a Vacation Rental Property — New York, October 2024–April 2025 (CDC: MMWR) Notes from the Field: Case of Legionnaires Disease Associated with a Home Device Used to Mix Powdered Infant Formula — United States, 2025 (CDC:MMWR) Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCErandomized clinical trial (CMI: Clinical Microbiology and Infection) FDA approves first oral carbapenem therapy for complicated urinary tract infections (FDA) Oral Tebipenem Matched IV antibiotic for complicated UTIs in Phase III Trial (MEDPAGE Today) US FDA approves GSK's oral antibiotic for drug-resistant UTIs (Reuters) Anti–Methicillin-Resistant Staphylococcus aureus (MRSA) Cephalosporins Plus Daptomycin as Initial Therapy for MRSA Bacteremia: Does a "Hit Hard and Fast" Strategy Improve Outcomes? (CID) Fungal The Last of US Season 2 (YouTube) Oral Wash PCR Improves the Diagnosis of Pneumocystis Pneumonia in Immunocompromised Patients Without HIV: A Prospective Multicenter Study (CID) Miscellaneous Foodborne Disease Outbreaks Associated with Marine Toxins — Foodborne Disease Outbreak Surveillance System, United States, 2011–2023 (CDC: MMWR) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #108 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/21 – 6/3/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D (NEJM) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (CMI: Clinical Microbiology and Infection) Chikungunya Vaccines for Travelers: Unanswered Pragmatic Questions Persist (JID) Bacterial Early Discontinuation of Empiric Antibiotics in Pediatric Haploidentical Hematopoietic Cell Transplant Recipients with Febrile Neutropenia (CID) Methicillin-Resistant Staphylococcus aureus Nasal Swab Utilization as a Predictor for Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID) Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial (CID) Fungal The Last of US Season 2 (YouTube) Donor-derived and nosocomial-acquired Candida auris transmission involving solid organ transplant recipients (Infection Control and Hospital Epidemiology) Parasitic Development of a Phase 1 Cryptosporidiosis Controlled Human Challenge Model in Healthy Volunteers Using Current Good Manufacturing Practice Cryptosporidium Parvum Oocysts and Conducted Under an Investigational New Drug Application (JID) Miscellaneous Childhood VaccineHesitancy(NEJM) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement </stron
On episode #106 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/23 – 5/6/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Andes hantavirus outbreak in cruise ship, 11 May 2026(European Centre for Disease Prevention and Control) 2026 Multi-country Hantavirus Cluster Linked to Cruise Ship (CDC: Health Alert Network) "Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) We Dissent: Lessons From the 2025 Community-Acquired Pneumonia Guidelines (CID) Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient (OFID) Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID) Bacterial Performance of a rapid, visual fingerstick serology self-test for Helicobacter pylori detection and typing: A prospective multicenter diagnostic accuracy study (CMI: Clinical Microbiology and Infection) Real-world effectiveness of 20-valent pneumococcal conjugate vaccine against all-cause outcomes among Medicare beneficiaries aged 65 years and older in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Beta-Lactam plus Azithromycin or Doxycycline versus Fluoroquinolones in Hospitalized Adult Patients with Community-Acquired Pneumonia: A Systematic Review and Network Meta-Analysis (OFID) Syphilis and the risk of stroke: a nationwide, population-based matched cohort study (CMI: Clinical Microbiology and Infection) Reducing Bacterial Contamination of Blood Bags with a Double Knot (NEJM) Effectiveness and safety of daptomycin versus vancomycin in methicillin-resistant Staphylococci left-side infective endocarditis. Results from a nationwide prospective multicenter cohort. (CMI: Clinical Microbiology and Infection) Fungal The Last of US Season 2 (YouTube) <a href= "https://link.springer.com/articl
On episode #105 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/9 – 4/22/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients (NEJM) Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir (NEJM) Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP) Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection (NEJM) A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage (JID) First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID) Bacterial Tetanus Surveillance — United States, 2009–2023 (CDC: MMWR) Notes from the Field: Tetanus in Four Children — Idaho, Minnesota, Missouri, and Wisconsin, 2024 (CDC: MMWR) Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults (JAMA) Efficacy and safety of vancomycin versus 13 alternatives in MRSA-confirmed skin and soft tissue infections: a meta-analysis of 39 randomized controlled trials (Infection) Methicillin-Resistant Staph Aureus (MRSA) Nasal Swab Utilization as a Predictor for MRSA Skin & Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID) Practice variation, outcomes and definitions of suppressive antimicrobial therapy for prosthetic joint infections: a systematic review and expert consensus statement (CIC) Efficacy and safety of VPM1002 and Immuvacin preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial) (BMJ) Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis (CID) Do C-Reactive Protein Measurements Predict Treatment Failure in Native Vertebral Ost
On episode #104 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/26 – 4/8/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis (Neurology) Bacterial Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study (CID) Inhaled Antibiotics to Treat Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis (Critical Care Medicine) ATS/IDSA 2016 Clinical Practice Guidelines for the Management of Adults With Hospital-Acquired and Ventilator-Associated Pneumonia (ISDA) Risk of Invasive Meningococcal Disease in Children Aged American Society of Breast Surgeons, Society of Breast Imaging, and College of American Pathology 2025 Guidelines for the Management of Infectious and Inflammatory Lesions of the Breast (JAMA Surgery) Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR) Effectiveness of Doxycycline in Combination With Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: A Causal Inference Study (OFID) Reply to Dissent: Guidelines for Management of Community-Acquired Pneumonia (CID) VancObituary: A summary of a life well lived and a death well timed (Journal of the Pediatric Infectious Diseases Society) Reports of My Demise Have Been Greatly Exaggerated (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Parasitic Red Blood Cell Exchange Transfusion for Severe Babesiosis (JAMA Internal Medicine) Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply (CID) Artesunate Treatment of Severe Malaria in Nonendemic Countries: When, Where, How, and What Now? (CID) Attention for Compliance: Visual Media in Second World War Anti-Malaria Efforts (AJTMH: American Journal of Tropical Medicine and Hygiene) Sc
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