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Infectious Disease Puscast: Daily Summaries Delivered
by Vincent Racaniello
A review of the infectious diseases literature from the previous two weeks.
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- 1 weeks ago37 min
Infectious Disease Puscast #107
On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement </stron
- 3 weeks ago40 min
Infectious Disease Puscast #106
On episode #106 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/23 – 5/6/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Andes hantavirus outbreak in cruise ship, 11 May 2026(European Centre for Disease Prevention and Control) 2026 Multi-country Hantavirus Cluster Linked to Cruise Ship (CDC: Health Alert Network) "Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) We Dissent: Lessons From the 2025 Community-Acquired Pneumonia Guidelines (CID) Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient (OFID) Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID) Bacterial Performance of a rapid, visual fingerstick serology self-test for Helicobacter pylori detection and typing: A prospective multicenter diagnostic accuracy study (CMI: Clinical Microbiology and Infection) Real-world effectiveness of 20-valent pneumococcal conjugate vaccine against all-cause outcomes among Medicare beneficiaries aged 65 years and older in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Beta-Lactam plus Azithromycin or Doxycycline versus Fluoroquinolones in Hospitalized Adult Patients with Community-Acquired Pneumonia: A Systematic Review and Network Meta-Analysis (OFID) Syphilis and the risk of stroke: a nationwide, population-based matched cohort study (CMI: Clinical Microbiology and Infection) Reducing Bacterial Contamination of Blood Bags with a Double Knot (NEJM) Effectiveness and safety of daptomycin versus vancomycin in methicillin-resistant Staphylococci left-side infective endocarditis. Results from a nationwide prospective multicenter cohort. (CMI: Clinical Microbiology and Infection) Fungal The Last of US Season 2 (YouTube) <a href= "https://link.springer.com/articl
- Apr 28, 202646 min
Infectious Disease Puscast #105
On episode #105 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/9 – 4/22/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients (NEJM) Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir (NEJM) Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP) Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection (NEJM) A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage (JID) First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID) Bacterial Tetanus Surveillance — United States, 2009–2023 (CDC: MMWR) Notes from the Field: Tetanus in Four Children — Idaho, Minnesota, Missouri, and Wisconsin, 2024 (CDC: MMWR) Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults (JAMA) Efficacy and safety of vancomycin versus 13 alternatives in MRSA-confirmed skin and soft tissue infections: a meta-analysis of 39 randomized controlled trials (Infection) Methicillin-Resistant Staph Aureus (MRSA) Nasal Swab Utilization as a Predictor for MRSA Skin & Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID) Practice variation, outcomes and definitions of suppressive antimicrobial therapy for prosthetic joint infections: a systematic review and expert consensus statement (CIC) Efficacy and safety of VPM1002 and Immuvacin preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial) (BMJ) Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis (CID) Do C-Reactive Protein Measurements Predict Treatment Failure in Native Vertebral Ost
- Apr 15, 202653 min
Infectious Disease Puscast #104
On episode #104 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/26 – 4/8/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis (Neurology) Bacterial Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study (CID) Inhaled Antibiotics to Treat Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis (Critical Care Medicine) ATS/IDSA 2016 Clinical Practice Guidelines for the Management of Adults With Hospital-Acquired and Ventilator-Associated Pneumonia (ISDA) Risk of Invasive Meningococcal Disease in Children Aged American Society of Breast Surgeons, Society of Breast Imaging, and College of American Pathology 2025 Guidelines for the Management of Infectious and Inflammatory Lesions of the Breast (JAMA Surgery) Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR) Effectiveness of Doxycycline in Combination With Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: A Causal Inference Study (OFID) Reply to Dissent: Guidelines for Management of Community-Acquired Pneumonia (CID) VancObituary: A summary of a life well lived and a death well timed (Journal of the Pediatric Infectious Diseases Society) Reports of My Demise Have Been Greatly Exaggerated (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Parasitic Red Blood Cell Exchange Transfusion for Severe Babesiosis (JAMA Internal Medicine) Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply (CID) Artesunate Treatment of Severe Malaria in Nonendemic Countries: When, Where, How, and What Now? (CID) Attention for Compliance: Visual Media in Second World War Anti-Malaria Efforts (AJTMH: American Journal of Tropical Medicine and Hygiene) Sc
- Mar 31, 202641 min
Infectious Disease Puscast #103
On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM) Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID) Bacterial Eagle effect (Wikipedia) THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM) Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine) Caring for Adult Patients With Sepsis (JAMA) Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine) Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine) Caring for Pediatric Patients With Sepsis (JAMA) ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians) Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA) Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications) Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Fungal The Last of US Season 2 (YouTube) Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID) Clinical and Radiological Predictors of <a href= "https://academic.oup.com/ofid/article/13/3/ofag137/8524191?utm_source=advanceaccess&utm_campaign=ofid&utm_medium=
- Mar 19, 202637 min
Infectious Disease Puscast #102
On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Measles Outbreak — New Mexico, 2025 (CDC: MMWR) Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID) Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR) Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine) Bacterial Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID) Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID) Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID) WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO) Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID) Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID) Fungal The Last of US Season 2 (YouTube) Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID) Parasitic Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID) Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID) Miscellaneous Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine) Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID) Possible <a href= "https://www.clinicalmicrobiologyandinfection.org/article/S1198-743X
- Mar 3, 202643 min
Infectious Disease Puscast #101
On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID) Tecovirimat for the Treatment of Mpox (NEJM) Bacterial Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR) Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID) Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy) Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID) Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance) Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection (JAMA Network) Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM) Fungal The Last of US Season 2 (YouTube) Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID) Parasitic State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID) Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases) Miscellaneous Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN) First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
- Feb 18, 202637 min
Infectious Disease Puscast #100
On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS) Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM) Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID) Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM) Bacterial Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN) Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID) US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature) Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR) Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases) Parasitic Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases) Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene) Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
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