Irsfeld Pharmacy: The Optimal You Podcast

Episode 055: Hormones, Cortisol & The Truth About Menopause

February 27, 2026·47 min
Episode Description from the Publisher

In this episode of the Optimal You Podcast, Pharmacist Steve Irsfeld sits down with Nurse Practitioner Bethany Mello of Advanced Specialty Care in Nampa, Idaho, to have an honest and informative conversation about hormone therapy, perimenopause, and menopause. Many women are told their labs are “normal”, yet they don’t feel normal at all. Fatigue, poor sleep, anxiety, weight gain, mood changes, brain fog, and low libido are often dismissed as just part of aging. But are they? Bethany shares her journey into functional medicine and explains how she evaluates hormones differently, focusing on optimal levels rather than just “within range” results. The conversation covers: The early signs of perimenopause Why progesterone often declines first The role of cortisol and stress in sleep and energy Differences between bioidentical hormones and synthetic options A clearer look at the Women’s Health Initiative and how it changed hormone therapy conversations Practical nutrition and supplement strategies that support hormone balance This episode is designed to educate and empower, helping women understand that they are not “crazy,” and that feeling well is possible at every stage of life. If you’ve been told everything is normal but you still don’t feel like yourself, this discussion offers clarity, context, and hope. As always, this podcast provides general educational information and is not a substitute for personalized medical advice. If you have questions about your own health, speak with your healthcare provider. Special Offer: As a thank-you for listening, use code Podcast55 at checkout in our online store for 25% off one product of your choice (valid for 60 days after airing). Be vigilant about your health and keep moving toward your Optimal You.

Podzilla Summary coming soon

Sign up to get notified when the full AI-powered summary is ready.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.

Listen to This Episode

Get summaries like this every morning.

Free AI-powered recaps of Irsfeld Pharmacy: The Optimal You Podcast and your other favorite podcasts, delivered to your inbox.

Get Free Summaries →

Free forever for up to 3 podcasts. No credit card required.