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by Latent.Space
The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al.
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- 2 days ago1h 41m
Academia is for Ambition — Alex Zhang, MIT
Last call for regular tickets for AI Engineer NYC! As an exclusive for Latent Space subscribers, the first 30 of you can take a 30% off code if it helps - for new tickets only, no refunds! See you in 2 weeks!While we tend to cover industry on the pod, every so often we celebrate a clearly emerging superstar PhD. In 2024 we featured Shunyu Yao, who went on to build Operator at OpenAI and is now Chief AI Scientist of Tencent. In 2025 we featured Jack Morris, who went on to cofound Engram at $600m and is now a leading voice on continual learning. This year we are proud to feature the work of Alex Zhang of MIT.From GPU kernels and KernelBench to Recursive Language Models, Mismanaged Geniuses, and massive multi-agent swarms, Alex Zhang is exploring how much capability we’re leaving on the table by wrapping increasingly powerful models in primitive systems. RLMs took over the timeline early this year:and an RLM based harness was the first to ~solve ARC-AGI-3 before OpenAI’s Astra:and is even today, influencing new research that has more extreme implications than RLMs:We go deep on GPU Mode and AI-written kernels, research taste and why academics should take bets industry labs won’t, GEV and alternatives to the standard autoregressive language model, and the idea of harnesses as compositional generalizers. Alex explains RLMs, context offloading, programmatic subagent calling, Prime Agent, persistent subagents, and why the “language model” of the future may actually be an invisible swarm of agents underneath a simple interface. We also discuss OpenAI’s massive agent experiments, Kimi swarms, open-ended research at Sakana AI, speculative programmatic tool calling, capability overhang, Neuralese, and where Alex thinks the next big research opportunities may lie.We discuss:* Why AI-generated GPU kernels still leave substantial room for human expertise* How one expert insight can potentially replace enormous amounts of brute-force token search* Why PhD students should take research bets that initially look trivial, weird, or pointless* What SWE-bench, RLMs, ReAct, and Quiet-STaR reveal about research taste* GEV and why a language model does not have to mean an autoregressive text-to-text decoder* Why Claude Code, Codex, and Pi are structurally more similar than they look* How harness design can improve compositional generalization across tasks and domains* RLMs: context offloading, code execution, recursive subagents, and shared memory* Prime Agent, continual harnesses, and persistent agent-to-agent communication* Why the model you query in the future may secretly be an entire swarm or scaffold* OpenAI’s 10,000-agent experiment, 130B output tokens, and ~$40M-equivalent problem solving* Why much of an agent swarm may be wasted search — and why convergence is still hard* Kimi versus OpenAI and different approaches to multi-agent systems* Open-endedness, Sakana AI, and finding hidden gems in enormous amounts of generated work* Why current frontier models may already have a large capability overhang* Speculative programmatic tool calling and overlapping tool execution with generation* Whether English, code, or an entirely new “Neuralese” constrains how models reason
- 3 days ago39 min
Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week
Three months ago Dwarkesh, who has been posting incredible blogs and episodes about RL, posted a framing question for his video essay on RLVR which upset a lot of Computer Use folks:We are no strangers to learning in public and are no strangers to the stress of getting things wrong when you have a big platform. However, we were at Anthropic for the Computer Use launch, there for Claude Cowork with the first big podcast on it, organized the first Computer Use track at AIE presenting the state of the art, and were close to the OpenAI-Sky Software acquisition that now powers the complete domination of computer use that Codex enjoys today. This is why we’re excited to bring you today’s first guest, Ari Weinstein, cofounder of Sky and now leading all the amazing CUA progress that casuals might miss:Ari explains why Computer Use is now “180 degrees different” from where it was months ago, how agents are learning to debug and recover from failures, why combining screenshots with accessibility data, the DOM, Playwright, and generated code changes the speed equation, and why the next frontier is making agents literally superhuman at using software.OpenAI clones JevIn the second half, Nikunj Handa from OpenAI’s API team breaks down the new developer stack: async tool calling, mid-turn steering, WebSockets, UltraFast inference, the Decisions API, prompt caching, pre-warming, compaction, and the Agents API. Given that we were the first Jev podcast, we particularly focus on the unusually fast sprint on the Decisions API:And why it is just a Luna wrapper for now but the team is motivated and egoless enough to clone what they consider to be good patterns.We discuss:* Why OpenAI thinks Computer Use has changed dramatically in just the last few months* Dots and what changes when every agent gets its own Linux computer* Why Computer Use can now complete some tasks faster than the average human* The path from human-level to “literally superhuman” computer use* Why modern agents are much better at debugging and recovering from failure* How screenshots, accessibility trees, the DOM, Playwright, and generated JavaScript work together* App Shots and why they give models much richer context than ordinary screenshots* Why Computer Use can close the loop between writing software and testing it* Trust, permissions, and safety when agents can make payments and operate websites* Async function calling and why models no longer need to stop reasoning while tools run* Mid-turn steering, WebSockets, and the architecture behind more responsive agents* UltraFast inference and how OpenAI is pushing frontier models toward much lower latency* The rapid internal story behind the Decisions API* Why Decisions API is more than structured outputs at low latency* GPT Live, fast tool calling, and real-time computer control* How OpenAI is already using Decisions API for support classification and internal workflows* Longer prompt caching, cache pre-warming, and cache-aware applications* Server-side compaction vs manual compaction for long-running agent threads* What should live inside an Agents API versus a developer’s own harness* OpenAI as an “AI cloud” and the search for higher-level primitives beyond raw model APIsAri Weinstein* Product & Engineering, Computer Use at OpenAI* X: https://x.com/AriX* LinkedIn: https://www.linkedin.com/in/weinsteinari
- 4 days ago1h 32m
Claude Code’s Next Era — Thariq Shihipar, Anthropic
We are excited to have Anthropic share their latest AI x Finance work at AI Engineer New York, coming up in 2 weeks!In case you’ve been under a rock, here’s a non-exhaustive list of what Anthropic has been shipping since closing the largest fundraise of all time in May at $47B ARR:* June: Launched Claude Tag and Sonnet 5 and Fable 5* July: Opus 5, /checkup. crossed $65B ARR* Last month: Fable/Mythos 5.1, and EFS (upcoming pod)* IPO target $2T, end 2026 ARR estimated $100B* Cowork/chat merged before did* Claude Mods* Dario endorses the same Pacing the Frontier message cosigned by all labs* Last week: Opus 5.5, Plugins portal, Cloud Sessions/Claude Projects* Today: Sonnet 5.5!Today’s episode should catch you up, with Thariq Shihipar, the explainer-king of Anthropic, who we last caught up on Fable launch day with The Field Guide to Fable:The Future of Mutable SoftwarePay special attention to Claude Mods (especially the cheatsheet):In general this is also the inverse of the other viral tweet from Thariq:Cloud Brain, Local HandsAnd give a try to Claude Projects:The “hands” terminology is not just an analogy for the local/cloud paradigm that is being built up at frontier coding agent companies like Cognition, but is ALSO particularly relevant to the safety systems discussions that we’ll be discussing with Anthropic in an upcoming episode as they prepare to pace to frontier with responsible AI deployment.For those who want Thariq’s writing tips we teased at the start of the pod, watch the full video here:From the rapid rise of Claude Code to a future where agents can rewrite their own harnesses, collaborate across teams, and operate across cloud and local environments, the way we build software is changing extraordinarily fast. In this episode, Anthropic’s Thariq Shihipar joins swyx and Vibhu to unpack how power users are actually working with Claude Code today, why prompting remains a high-skill discipline, and where Anthropic thinks the agent harness is headed next.We go deep on Claude Code’s evolving interface: Ask User Question and elicitation, artifacts as persistent generative interfaces, Claude Tag for multiplayer agent workflows, Projects, model effort, implementation notes, and the new Claude Mods system for customizing the harness itself. Thariq explains why Claude.md may eventually disappear, why the smartest model could also become the cheapest model for many tasks, and why mutable software could become a new paradigm for how applications are built and customized.The conversation then turns to agent security and Anthropic’s “Pacing the Frontier” argument. Thariq walks through recent incidents where
- 1 weeks ago1h 20m
OpenRouter: from Seed to Stripe — with OpenRouter’s Alex Atallah & AMP’s Anjney Midha
From the earliest days of open-weight models to becoming the neutral routing layer for more than 10 million developers, OpenRouter is one of the clearest bets that the future of AI will be multi-model. In this episode, OpenRouter co-founder & CEO Alex Atallah, with AMP’s Anjney Midha returning with swyx to unpack how OpenRouter emerged from the first wave of Llama, Alpaca, Mistral, and Midjourney, why model diversity mattered before it was consensus, and how a company dismissed as “just a wrapper” became critical infrastructure for the AI ecosystem.We go deep on the product and distribution lessons behind OpenRouter: why model labs can spend billions training a checkpoint and still struggle to get it into developers’ hands, how Mistral helped prove the value of a competitive inference marketplace, why OpenRouter chose focus over expanding into fine-tuning, memory, and other adjacent products, and how its rankings became a real-time map of how AI usage was changing. Alex also explains OpenRouter’s early experiments with model fusion, why they deleted the first version and brought it back years later, and how the platform grew to more than 10 trillion tokens per day.Finally, Anjney explains why Stripe and OpenRouter fit together, why token fraud may become one of the defining security problems of the AI economy, and why the next wave of fraud won’t just come from humans but from autonomous agents attacking increasingly valuable token flows.We discuss:* Why OpenRouter bet early that no single AI model would win everything* Alpaca, Llama, and open models becoming impossible to ignore* Why Discord’s early AI deployments exposed the limitations of closed models* Why model labs can spend billions on training and still fail at distribution* How OpenRouter became a neutral distribution layer for model developers* Why VCs dismissed OpenRouter as “just a marketplace” or “just a wrapper”* The Mistral price war and the first real proof of an inference marketplace* How Midjourney scaled through Discord and what it taught the AI ecosystem* Why crypto infrastructure became a dress rehearsal for generative AI* OpenRouter vs. LM Arena and why their missions are fundamentally different* Why focus became one of OpenRouter’s biggest strategic advantages* Anthropic’s early focus on AI pair programming and coding* The OpenRouter products that were prototyped but never launched* MOM, OpenRouter’s early Mixture of Models experiment* Why model fusion failed in 2024 — and why it works much better now* How OpenRouter’s leaderboard became a live map of the AI industry* OpenClaw, auto-routing, and agents reshaping AI usage* How OpenRouter reached 10+ trillion tokens per day* Why inference gateways are increasingly becoming targets for fraud* Why Stripe’s fraud infrastructure is strategically important to OpenRouter* The coming rise of agentic fraud and attacks on the token economy* What changes and what stays the same as OpenRouter joins StripeAlex Atallah* LinkedIn: https://www.linkedin.com/in/alexatallah/* X: https://x.com/alexatallah* Website: https://alexatallah.comAnjney Midha* LinkedIn: https://www.linkedin.com/in/anjney/* X: https://x.com/AnjneyMidha* AMP: https://www.amppublic.com/Timestamps00:00:00 Introduction00:02:12 Alpaca, Llama, and the Multi-Model Bet00:06:04 Discord, Open Models, and OpenRouter’s Origins00:14:28 Why “One Model Wins” Was the Wrong Bet00:17:27 Why Model Labs Struggle With Distribution00:23:0
- 1 weeks ago1h 36m
Runway’s WorldPrompt and the Engineering of Real-Time Worlds
Earlier this month, world model company Runway introduced GWM Worlds 2, a research preview that “turns high-fidelity video and audio generation into real-time interactive simulation.” Runway calls this an “autoregressive diffusion” model; with autoregressive describing how it generates over time.One new feature in particular caught our eye: WorldPrompt, a proposed input format for specifying a generated world and the actions within it. It allows you to fix some aspects of a simulated environment — including the first frame — and then create a series of timestamped events. The events, or actions, can even be prompted in real-time.To understand the implications of WorldPrompt, we spoke to Kamil Sindi, Runway’s CTO, and Robin Kahlow, its Principal Research Scientist for generative video and multimodal AI. We also have exclusive comments from Anastasis Germanidis, co-founder & co-CEO of Runway, courtesy of a podcast swyx and Vibhu did with him.Who’s building real-time interactive world models?First, some context about world models that can generate interactive video and audio in real-time.Runway is reportedly valued at $5.3 billion, based on its most recent fund raise of $315 million in February. Its first release, GWM Worlds, was launched last December.Alongside Runway, there are several other notable projects in this domain: Google DeepMind’s Genie 3 (which also generates at 720p and 24 fps), Odyssey-2 Pro, and World Labs’ RTFM (Real-Time Frame Model). We’ve summarized their differences in the following table:Given the complexity and massive latency demands of real-time video and audio generation (which we’ll get into below), all of the projects listed above have limitations. For instance, Google notes that Genie 3 “can currently support a few minutes of continuous interaction, rather than extended hours.”But as our interviews with Runway show, real progress is being made.The central idea of WorldPromptWorldPrompt, a new feature in GWM Worlds 2, helps differentiate Runway from its competition. You can think of it as a control layer for characters, cameras and the environment. As Kahlow put it, it’s a way to “control all the different subjects in the world” — similar to a computer game.“Like, if there’s an NPC [Non-Player Character] somewhere, the NPC might walk up to you and say something. So you could achieve the same thing with this kind of model, where you can have very detailed control over everything in the scene.”As the name suggests, WorldPrompt is a prompting mechanism — not a programming language. So, unlike virtual world games like Minecraft or Roblox, GWM Worlds 2 doesn’t offer scripting capabilities or the ability to control state. But there’s a power to that, as Sindi pointed out.“You can create promptable worlds on-demand with video and audio in sync, across all these different domains and environments. That’s not a distant-future hypothetical thing,” he said.But there are also limitations to prompting a world model. We asked how reliably the model would follow an instruction to create, for example, a law of gravity or a certain ability in a character?“Yeah, so it’s a research preview,” Kahlow replied. “So it’s not perfect, of course, and there are still flaws. It really depends on how difficult the action is. I would say movement works quite reliably.”Sindi added that more training plus scaling the data and models is resulting in “better following.”How a video model becomes a real-time runtimeDespite the current limitations of GWM Worlds 2 — especially if you compare it to pre-designed and scriptable worlds like Minecraft or Roblox — the true promise of world models like Runway is that they’ll eventually lead to fully self-generated, real-time games and experiences. Which is an extremely hard engineering problem, as Kahlow reminded us.“There are two
- 1 weeks ago1h 31m
🔬Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics)
The OpenAI → Hugging Face attack has people asking “what else do we need to worry about?” and Anthropic’s filters flag two things: cyber-security and biology. The natural question is: what about bio-security, then? Clem Delangue argues that cyber-warfare defensive capabilities need to be open and to keep pace with frontier models’ attack capabilitiesRadical Numerics co-founder Eric Nguyen sat down with us and explained why the same models that increase biological capability can also keep defense from falling behind.Building a virus from scratchWhile he was at Stanford, Eric couldn’t get traction on Genomic Language Models (GLMs) for a long time. Biologists didn’t believe it would work, didn’t think they could verify the output, and didn’t see important applications beyond what they could already do. He kept pushing, eventually helping lead the development of Evo and contributing to Evo 2 at Arc Institute. Those models were later used by a separate Arc/Stanford team to generate entire bacteriophage genomes that were synthesized into functional viruses!Long context unlocks biological intelligenceEarly ChatGPT spit out poems and email, and early DNA language models like Evo and Evo-2 could build a genome from scratch. DNA is different, however, from natural language in that it has a very small alphabet (4 characters ACTG) and that its sequences are very long:* 60K for an average human gene* long being up to 2.3M* the whole human genome around 3B.Innovation in long-context models made this possible about 3 years ago (footnote: striped hyena), long before the frontier labs were building 1M+ context models.Now Eric and other AI x Bio luminaries have founded Radical Numerics to build and scale GLMs to tack a wide range of biological problems, extending well beyond generating DNA.Thinking in DNATheir GLMs already do pretty well with RNA and protein because there are clear markers in the DNA sequence for genes (RNA sequences the perform many functions) and specific genes that encode proteins. This means that the models already generalize to multiple “languages,” before even attempting to train in other modalities, such as 3d protein structure, epigenetics and natural language.If a model thinks in the DNA language, maybe it understands the imprint that environment left on different genomes as well? Perhaps the model has learned the functional relationship between different sequences, and could extrapolate to new sequences based on that?And so what we wanted to showcase was that if we show the model progressively better RNAs in a series of steps with its score, right? So you have like low scores first and then you gradually move up the chain. Can the model continue that trajectory on its own? And then in the final step, does it self optimize to a point where it's like the best score it can get? That was the experiment. Can we do that? And so we took a data set, a large data set of aptamers. We held out a portion of the best performing ones and we showed it only the lower ones, but then we ranked it, right? So we showcase lower scores with the RNA aptamers and then progressively got higher, and then ask the model to just like continue with that pattern. And it turns out it was able to recapitulate some of those higher scores that we had not shown it yet.So, voila: chain-of-thought, thinking in DNA!The arms raceBut much as long-context inference, chain-of-though and multi-modal perception unlocked sophisticated reasoning in natural language LLMs, these capabilities in GLMs are enabling increasingly sophisticated “biological intelligence,” and along with it, greater danger.According to Eric, defense is currently losing this battle, but Radical Numerics argues to push the frontier harder!I won’t spoil the details for you. In the episode we talk in detail about:* Biosecurity as an arms race — and how defense can keep up* The genome as the imprint of the environment on DNA* Going truly multi-modal* How chain-of-though works when you “think” in the language of DNA This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.latent.space/subscribe
- 1 weeks ago2h 1m
🔬 An Oscar, Two Asteroids, and the Algorithm in Your sklearn: John Platt on AI for Science
How often do you get to talk to a guest who has both an Academy Award and who invented textbook machine learning algorithms? John Platt has an Oscar, two textbook algorithms, two named asteroids, and an Erdos-Bacon number of 6. This was easily the most fun bio of all the guests we’ve read to date. And the result was an epic and fun chat covering Google’s Empirical Research Assistance (ERA), how AI can help battle climate change, and tons of great stories about the co-evolution of science and AI.John’s colleague Dave Bacon likes to tease John that his career has been defined by being twenty years early to the next big thing. This may be convolutional neural networks (some credit him with coining the term), fusion research, quantum computing. John and Google have been working on solving some of humanity’s hardest problems with AI and computation for well over a decade now. Recently John and his team set their sights on using AI to solve any scientific problem that can be written down as a score.Google’s Empirical Research Assistance (ERA)John’s team has taken on many hard scientific problems over the years. In solving these, they noticed a pattern, many scientific problems can be reduced to what John calls a “scoreable task”. Once you have the score function, the goal is to find some code that maximizes the score. The hard part is in formulating the score, but once you have the score finding the maximizer can still be quite a lot of effort.John’s team set out to automate solutions to this general problem. This came out of the idea of an “auto-Kaggle” AI, which can solve any Kaggle problem you can throw at it. Kaggle is owned by Google, so all the data was ready and easily available to them!The result is Google’s Empirical Research Assistance or ERA (paper, github, blog). ERA is surprisingly simple conceptually. Gemini (or your LLM of choice) keeps a running tree of past experiments (notebooks) and where they’re going. It’s a close cousin of Monte Carlo Tree Search: at each iteration the Upper Confidence Bound rule picks which notebooks are most promising to mutate. This is optimistic, not greedy, so sometimes even the fifth-best notebook gets chosen. Gemini then proposes mutations for each one, about ten at a time. The history of each branch is shared, so different leaves can learn from each other.“It’s almost like having a hyper-eager grad student who doesn’t sleep.”Evolutionary algorithms have been around since the 70s, but this works because Gemini actually knows where to look! What’s even more interesting is that there was a step change between Gemini 2.0 and 2.5, and this went from just not working to working great.ERA is so powerful that John and his team solved many outstanding problems with it, resulting in at least ten papers. Some of these were climate change related, which we talk about in the next section.So, we had to ask: if you have an optimization god how do you avoid fooling yourself? John’s answer is that ERA provides predictive models. It’s up to the scientist to make sure they’re truly descriptive. Some of this just involves good old-fashioned careful machine learning science. “It’s a power tool. It can slice your fingers off.” This led to some fun discussion about Kaggle competitions, and the fun ways people can overfit to datasets without meaningfully solving the problem you actually care about: Google’s contrail-detection competition was won by entrants who noticed a half-pixel error in the labels (is the origin at the corner of the pixel or the center?) and this turned out to be a p
- 1 weeks ago2h 20m
Jev: System One models for Prod, not God — with Diogo Almeida, CEO, TypeSafe AI
Tickets for AIE NYC now open, and apply for the invite-only AIE CODE. Join us!We have an unusual relationship with today’s guest: for years since coauthoring the InstructGPT paper, Diogo Almeida had been saying that API-available frontier models have been going down the wrong path, everything from the alignment to refusals to reliability perspectives, that we have dropped every mode other than autoregressive chat-tuned LLMs because of the overwhelming success of ChatGPT.In a launch video now viewed ~40M times (by comparison, GPT4o was 22M, Fable 5 was 15M, Navier Stokes was 74M, and 6 Astra was 137M), Diogo introduced Jev and it immediately took over the AI timeline — we’ll skip full Jev explainers because your favorite AI influencer/educator has probably already done one. We also collected:* the official patterns and cookbooks you should see first, from Allie* Jev usecases* speed based - games and computer use* the voice + computer use example we discuss at 1h34 mins* voice + browser control* The must not miss Doom demo* Driving cars in games* Excalidraw* virtual try-ons* “Smart Games”/smart NPCs* guided responses in text messages* Jev for coding agents has an official guide * jev for linting* compacting tool calls* reasonable pushback from Theo - Diogo has published a note on the Tyranny of the KV Cache that you should read as a followup after the pod for Jev + coding agents, because of his belief that Cache Rules Everything* Programming Languages built atop Jev (Diogo’s fave)* Jev for analytics replay and user journey review* “dark data”* entity resolution* natural language search* “smart software”* a core goal of Jev is to “disappear into the background” - eg as unremarkable as regex* Jev as a judge* Jev memes* <a target="_blank" href="https://x.com/markjaquith/status/210
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About Latent Space: The AI Engineer Podcast
The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al.
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