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Lira Clinical Podcast - A SkinDepth Convo: Daily Summaries Delivered
by Lira Clinical
Join A SkinDepth Convo with Lira Clinical founders and skincare experts, Metaxia Dalikas and Francine Kagarakis. A show dedicated to educating and inspiring all those in the skincare industry and also for those of you interested in finding ways to improve yourself from the inside out. In each episode the show covers the latest skincare trends, scientific skincare protocols and ingredient technology to prevent and treat skin conditions including acne, pigmentation, rosacea and more. The show also focuses on the science behind anti-aging and maintaining ageless skin. Get tips on prevention and maintaining flawless skin and enjoy some entertaining conversation along the way. Have questions about skincare? We answer questions from listeners in every show. Submit your questions to skindepthconvo@liraclinical.com
Latest Episodes
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- 2 weeks ago
Skin Depth Ep 67 – May 18, 2026 – Wildtype & Lira Clinical: A Revolution in PDRN ft The WildType Team
In this groundbreaking episode of A SkinDepth Convo, hosts Metaxia Dalikas, Francine Kagarakis, and Anna Kagarakis are joined by the Wildtype team for an in-depth conversation on how biotechnology and regenerative science are transforming the future of skincare.Together, they explore the evolution of next-generation ingredients, from the growing interest in PDRN to Wildtype’s breakthrough innovation: Marine Cellular Complex, also known as Wild Salmon Stem Cell Conditioned Media. The discussion dives into the science behind cultivated salmon technology, how it has expanded beyond food innovation into advanced skincare applications, and what this means for the future of skin health and regeneration.This episode also highlights a true San Francisco Bay Area collaboration, bringing together visionary leaders in biotechnology and professional skincare to discuss what’s real, what’s next, and how science-backed advancements are redefining the industry. If you’re curious about regenerative ingredients, cutting-edge skincare science, and the intersection of biotech and beauty, this is a conversation you won’t want to miss.
- Apr 13, 20261h 0m
Skin Depth Ep 66 – April 13, 2026 – The Wellness Series: Virtual Fasting & The Magnificent Free 7 ft Dr. John Konstantin
In this episode of A SkinDepth Convo, hosts Metaxia Dalikas, Francine Kagarakis, and Anna Kagarakis explore the powerful connection between internal health and skin health, revealing why true radiance starts from within.From the role of the microbiome to liver function and cellular renewal, the conversation dives into how the body’s internal systems directly influence the skin’s appearance, resilience, and overall vitality. Drawing from their deep expertise and experience as founders of Lira Clinical, the hosts discuss the growing integration of wellness, esthetics, and medical science, and why modern skincare is no longer just skin-deep.They are joined by special guest Dr. John Konstantin, who helps connect the dots between internal health and lasting, visible skin results. Together, they unpack how a holistic, inside-out approach is shaping the future of skincare and empowering both professionals and clients to think beyond the surface.Tune in to discover how aligning internal wellness with advanced skincare can transform not just your skin, but your overall health.
- Dec 31, 202543 min
Skin Depth Ep 65 – December 31, 2025 – Purely Clinical 2025 Recap
Purely Clinical is more than an event; it’s an experience where education meets innovation and the future of skincare takes shape.Over the past year, the Lira Clinical owners traveled across the globe delivering advanced education, protocol-driven learning, and exclusive first looks at upcoming innovations, straight to the treatment room. We’re recapping standout moments from the tour stops and unpacking what attendees truly gained, from interactive sessions and protocol development to testing prototypes and influencing product launches before they hit the market.And of course, we’re teasing what’s ahead, because Purely Clinical 2026 is already shaping up to be something special. Join expert hosts and Lira Clinical founders Metaxia Dalikas and Francine Kagarakis for an inside look at the experience that’s redefining clinical education.
- Dec 19, 20255 min
BONUS - Skin Depth – December 19, 2025 – Funny Moments of 2025
As we close the chapter of 2025 and reflect on all the things we accomplished, let's not forget the funny moments. Relive the laughs, bloopers, and real behind-the-scenes chaos that made 2025 unforgettable.
- Dec 17, 20251h 24m
Skin Depth Ep 64 – December 17, 2025 – Best of 2025
From breakthrough launches to meaningful milestones, this episode of A SkinDepth Convo reflects on a year that shaped the future of clinical aesthetics. Join us as we revisit our defining moments, celebrating innovation, education, and the community that made it all possible.We look back on 2025, on a year of growth, innovation, and momentum, while setting intentions for what’s next.Tune in for a thoughtful recap of 2025 and a celebration of how far we’ve come together.
- Nov 25, 202535 min
Skin Depth Ep 63 – November 25, 2025 – Inclusive Skincare ft. SYNRG Owner, Gerline Jean-Louis
In this episode of A SkinDepth Convo, hosts Metaxia Dalikas, Francine Kagarakis, and Anna Kagarakis dive into the beauty and complexity of treating diverse skin tones. Skincare is never one-size-fits-all, and understanding the needs of every background, heritage, and Fitzpatrick type is essential for truly inclusive care.Joined by Licensed Esthetician Gerline Jean-Louis, owner of SYNRG and a renowned practitioner specializing in higher Fitzpatrick skin types, Gerline shares her passion for education and empowerment, and valuable insight into what makes deeper skin tones unique, the misconceptions that persist in the industry, and the most common challenges her clients face.Together, they explore how to better support global beauty through informed practice and how Lira Clinical’s innovative, adaptable formulations help achieve bright, balanced, glowing results for every complexion.Tune in for an inspiring, knowledge-packed conversation that celebrates diversity in skin health.
- Oct 28, 202549 min
Skin Depth Ep 62 – October 28, 2025 – Spooky Skin Care Stories
Things are getting spooky at A SkinDepth Convo! Hosts Anna Kagarakis, Metaxia Dalikas, and Francine Kagarakis are joined by the rest of the fabulous founders of Lira Clinical, Brenda Cumming, and Anna Konstantin, for a Halloween special you don’t want to miss.From real-life treatment room scares to lessons learned the hard way, these skincare pros share chilling (and hilarious) stories that remind us why education, safety, and the right products are no trick; they’re the ultimate treat.So grab your pumpkin spice latte, light that candle, and tune in… if you dare!
- Oct 20, 202539 min
Skin Depth Ep 61 – October 20, 2025 – Metaxia's Journey - Strength, Resilience & Skincare Through Breast Cancer
This October, in honor of Breast Cancer Awareness Month, we're sharing a deeply personal and inspiring story from Lira Clinical Co-Founder Metaxia Dalikas. As a breast cancer survivor, Metaxia opens up about her journey of courage, faith, and resilience, both in her personal battle and in her leadership of a global skincare company.In this powerful episode, Metaxia discusses her diagnosis and treatment experience, the challenges of balancing her health while running a business, and the incredible support she received from her family and Lira Clinical co-owners. She also shares expert advice on caring for your skin before, during, and after cancer treatments.Joining the conversation is fellow Lira Clinical founder and host Francine Kagarakis, who stood by Metaxia's side throughout her entire journey. Together, they offer hope, practical guidance, and inspiration for anyone facing similar challenges.
About Lira Clinical Podcast - A SkinDepth Convo
Join A SkinDepth Convo with Lira Clinical founders and skincare experts, Metaxia Dalikas and Francine Kagarakis. A show dedicated to educating and inspiring all those in the skincare industry and also for those of you interested in finding ways to improve yourself from the inside out. In each episode the show covers the latest skincare trends, scientific skincare protocols and ingredient technology to prevent and treat skin conditions including acne, pigmentation, rosacea and more. The show also focuses on the science behind anti-aging and maintaining ageless skin. Get tips on prevention and maintaining flawless skin and enjoy some entertaining conversation along the way. Have questions about skincare? We answer questions from listeners in every show. Submit your questions to skindepthconvo@liraclinical.com
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