Naked Scientists, In Short Special Editions Podcast

Sickle cell defeated malaria and opened up pastures new

July 14, 2026·8 min
Episode Description from the Publisher

Malaria has been killing humans for at least fifteen thousand years, and our DNA still carries the scars. Ninety percent of the world's malaria cases are in Africa. But this isn't just a modern health crisis. It's written into our evolutionary history. New research from the University of Cambridge reveals that early humans actively avoided malaria hotspots across Africa for tens of thousands of years. The archaeological record is striking: mosquitoes thrived where people didn't live. Until something changed. Around fifteen thousand years ago, a genetic mutation emerged in West Africa: the... Like this podcast? Please help us by supporting the Naked Scientists

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