
In this episode, Dr. Andy Cutler speaks with Dr. Thomas Schwartz about insomnia related to antidepressant discontinuation, including how rebound and withdrawal symptoms can emerge when tapering or stopping treatment. They review the underlying mechanisms, clinical risk factors, and how to distinguish discontinuation-related insomnia from relapse of depression or primary sleep disorders. The discussion emphasizes practical, evidence-informed strategies for safely tapering antidepressants and managing sleep disturbance in psychiatric practice. Thomas L. Schwartz, MD, is a Distinguished Teaching Professor at Norton College of Medicine, SUNY Upstate Medical University in Syracuse, New York. He is an award-winning educator deeply involved in medical student and resident training, as well as the development of continuing medical education in psychiatry. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at nei.global/spring Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: <span class= "NormalTextRun CommentStart CommentHighlightPipeRest CommentHighlightRest
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E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome

E282 - 2026 NEI Spring Congress Extended Q&A: Anxiety, Schizophrenia, and Postpartum Mood Disorders with Drs. Strawn, Correll, and Payne

E281 - ADHD, Hormones, or Aging? Sorting Out Cognitive Complaints in Women with Dr. Neill Epperson

E279 - Sleep in Bipolar Disorder: Clinical Insights with Dr. Holly Swartz
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