NTSB News Talk – Aviation Accidents, Safety Investigations & Pilot Lessons

Benadryl, Cannabis & the FAA No-Fly List: Fatal Lessons for Pilots

October 7, 2026·36 min
Episode Description from the Publisher

Episode 40 examines a wide range of recent accidents before focusing on a troubling pattern: pilots flying with impairing OTC medications or drugs in their systems.Max Trescott and Rob Mark begin with a fatal nighttime crash of C-GPTX, a Cessna 172 in Saskatchewan and the runway overrun of Eclipse 500 N816KD at Auburn, California. They also discuss Beech Travel Air N529RB, which was flown in repeated low-level circles about 100 feet above the Pacific before crashing into the ocean, raising the possibility of an intentional act.Preliminary reports include Piper Seneca N212ML, lost near the Bahamas in convective weather; C-IFBY, a Para-Ski VX powered parachute carrying three people even though its U.S. operation did not qualify under Part 103; and Lake Amphibian N6185V, which apparently ran out of fuel just miles from Ithaca.Final reports include a fatal VFR-into-IMC accident involving N9626K, a Piper PA-28 and the crash of Ameriflight Beech C99 N130GP after a partial engine-power loss.The episode closes with four fatal-accident reports involving the active ingredients in Benadryl and Zyrtec, or cyclobenzaprine, cannabis, or morphine. The takeaway is simple: “over the counter” does not mean “safe to fly,” and pilots need to understand the FAA’s medication waiting-period guidance. Max also explains why medication effects can undermine a pilot’s own self-assessment.

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