Perimenopause Simplified

126. Mood Swings & Anxiety: Could Estrogen Be The Missing Piece?

October 7, 2026·17 min
Episode Description from the Publisher

Estrogen often gets a bad rap, but it's one of the most powerful and protective hormones in a woman's body, especially in midlife. In this episode of Perimenopause Simplified, we're unpacking what estrogen does, how it changes after 40, and what you need to know about supporting it through perimenopause and beyond. Whether you're dealing with brain fog, vaginal dryness, or mood swings, this episode will help you understand whether low estrogen might be at play – and what you can do about it. We also dive into hormone replacement therapy (HRT), the different forms of estrogen available, and why progesterone is essential if you choose to supplement. Estrogen isn't the enemy; let's set the record straight.   What's covered in this episode: The benefits of estrogen for your brain, heart, bones, and mood How estrogen levels fluctuate and decline during perimenopause and menopause Signs and symptoms of low estrogen vs. estrogen excess When to consider estrogen HRT and the different types (patches, gels, Biest & more) Why progesterone is needed when taking estrogen HRT How to support healthy estrogen detoxification through liver, gut, and lifestyle strategies   ------------------------------------------------------------------------------------ SAVE $300 on Personalized Support! Stop guessing - and get real answers (and results) in The Perimenopause Method. This program has helped hundreds of women finally feel like themselves again - without the overwhelm. APPLY HERE by OCTOBER 23 and get $300 OFF on enrollment ------------------------------------------------------------------------------------   Links Mentioned: Ep. 31: How Endocrine Disruptors Impact Perimenopause For a deeper dive into estrogen, listen to Ep. 36: Estrogen: Why We Love It & Need It w/ Jill Chmielewski, RN, BSN   Connect with Claudia: Website  YouTube  Instagram  Facebook  Inquiries    Free resources:  👉6 Things Missing From Your Routine Labs That May Be Contributing to Your Anxiety, Mood Swings & Fatigue After 40 👉Mini Training: Why You're Exhausted, Moody & Gaining Weight After 40 (And What Actually Matters) 👉HRT Crash Course: What Every Woman 40+ Needs to Know Before Starting Hormone Therapy

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