The Gary Null Show - 10-6-26

HEALTH NEWS   Blueberries can modify the gut microbiome in older adults with mild depression Living environments and lifestyle factors may contribute to faster adult biological aging Too little salt may hurt memory just as badly as too much Regular walking is good for people with COPD, even if they live in areas with higher air pollution Study: Stroke Rates Nearly Doubled in Adults Under 55   Blueberries can modify the gut microbiome in older adults with mild depression Hinda & Arthur Marcus Institute for Aging Research & Beth Israel Deaconess Medical Center, September 30 2026 (Medical Xpress) A new pilot study found that older, sedentary adults who consumed blueberries daily showed a greater, more consistent reduction in depressive symptoms, along with minor changes in markers of gut microbial enzymes.   The preliminary data warrant further research into the link between blueberries, the gut microbiome and mood in older adults. Fiber and anthocyanins in blueberries have potential to modify the gut microbiome and metabolites that are relevant to depression in older adults.  Sedentary adults 65 and older with mild depressive symptoms were enrolled in a randomized, double-blind, parallel-arm, placebo-controlled pilot study. Participants consumed 48 grams (1.7 ounces) of blueberry powder per day (approximately two cups, or 475 milliliters, of fresh berries) or a matched placebo powder for three months. Within the blueberry group, there were statistically significant differences in the gene abundance of several enzyme commissions of the gut microbiome—including EC 3.6.3.31 Polyamine Transporting ATPase, which is involved in the production of the neurotransmitter gamma-aminobutyric acid (GABA).   Living environments and lifestyle factors may contribute to faster adult biological aging University of Jyväskylä (Finland), September 30 2026 (News-Medical) Researchers found that biological aging may accelerate already in early adulthood. In addition to lifestyle factors, environmental exposures and living environment may contribute to faster biological aging. In the study, childhood and adolescent lifestyle and environmental exposures explained approximately 28% of the variation in biological age at the age of 22.  Genetics, lifestyles and environmental factors shape how fast our bodies age. Biological aging begins already before birth, and it can progress faster or slower than chronological age. Faster biological aging increases the risk of developing age-related diseases earlier in life. In a longitudinal twin study researchers examined the exposome, the totality of lifestyle and environmental exposures, and its effect on biological age in young adulthood using machine learning models. In the study, the exposome was captured based on 186 lifestyle and environmental exposures, including lifestyle factors, surrounding greenness, air pollution, and living area sociodemographic factors. The researchers found that the measured childhood and adolescent exposures explained approximately 28% of the variation in epigenetic age at the age of 22. Smoking, alcohol use, and youth unemployment were associated with accelerated biological aging. In contrast, higher tree cover, vegetation index, and neighbourhood age structure predicted slower aging. The findings highlight the significant impact that living environments and social circumstances have on biological age already in youth.   Too little salt may hurt memory just as badly as too much Zhejiang University (China), October 5 2026 (Medical Xpress) Salt can make or break a dish. A little too much or too little can throw everything off, leaving even the most luxurious ingredients tasting off. But get the balance right, and salt can bring out the flavor in even the simplest ingredients. The brain relies on a similar balancing act for healthy function and memory. While we are aware of the ill effects of having too much salt, what happens when we consume too little?   A recent study compared how long-term low-salt and high-salt diets affected memory, gut health and brain health in mice whose guts were colonized with human gut bacteria. The researchers focused on the gut–metabolite–brain axis, examining how dietary salt alters gut bacteria and their chemical products, and how those changes signal back to the brain. Mice on either a low-salt or a high-salt diet struggled with memory, but through two different biological pathways. Compared with mice eating a normal amount of salt, they did worse on tests of short-term working memory and long-term recognition memory.  Inside the hippocampus, the brain's memory center, both diets lowered critical synaptic proteins like SYN1, PSD95 and BDNF and suppressed CREB activation. All of these are essential tools neurons use to build memories and ada