Ep. 137: “Tissue Specificity of miRNAs” Featuring Dr. Brian Brown

Guest: Dr. Brian Brown is a Professor at the Icahn School of Medicine at Mount Sinai. He discusses how his lab develops innovative technologies to study the immune system and advance new therapeutics, from T cell engineering to mRNA-based medicines. He also explores how microRNA-guided targeting can improve the precision of mRNA therapeutics, how different tissues shape immune responses, and the importance of effective science communication. Featured Products and Resources: Learn more about STEMCELL’s optimized protocols and reagents for immunotherapy research. Download this free conference toolkit to make the most out of your experience this conference season. The Immunology Science Round Up Sindbis in Cerebrospinal Fluid – Scientists have found evidence that Sindbis virus can invade the human central nervous system and cause neurological disease. A Skin–Lung Reflex – Activation of sensory neurons in the skin suppresses allergic airway inflammation through a vagus nerve–mediated neuroimmune reflex. Microbiome Enhances Cancer Immunity – Gut bacteria promote anti-tumor immunity by converting tryptophan into indoles that enhance immune responses and inhibit melanoma growth. Macrophages Drive Healthy Aging – Restoring macrophage clearance of senescent neutrophils reverses age-related decline across multiple organs in mice by blocking EP2 signaling. Image courtesy of Dr. Brian Brown <div class="wpb_text_column wpb_c