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by Chemist Confessions Inc.
Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science.The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a skincare routine, finding a serum that’ll ACTUALLY deliver, or just want to have a few laughs on some of the crazy things you see in skincare.
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Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions We are starting of this series with tinted sunscreens. Navigating this category can feel like an existential crisis because these formulas are highly dependent on specific skin types and coverage needs. In this episode, we categorize this year's contenders by pigment level—ranging from completely sheer fluids to high-coverage, foundation-like hybrids, while analyzing the formulation realities behind heavy textures, solvent loads, and the myth of the "universal tint".
We are officially diving into the sunscreen segment to break down a burning, highly technical question for anyone tackling stubborn dark spots: is iron oxide a non-negotiable must-have for your hyperpigmentation routine? Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions
We are reviewing five popular K-Beauty products to see if they actually live up to the hype. We break down the science behind different PDRN sources, explore the "50 peptides" marketing claims, and analyze clinical data to separate realistic skin improvements from clever lighting tricks. You will learn how these products perform on different skin types—from "sticky and drying" textures to clinical-grade results—so you can decide which formulas are worth your routine and which are just "science-flavored" fillers. Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 IOPE | XMD Stem III Clinical Recovery Serum 50ml: https://go.shopmy.us/p-56645998 MEDIHEAL | PDRN Lifting Serum: https://go.shopmy.us/p-56646034 DR.REJU-ALL | Advanced PDRN Rejuvenating Cream 20ml: https://go.shopmy.us/p-56646069 REJURAN | Rejuran Turnover Ampoule C-PDRN 0.5% Renewing Serum for Smooth Texture & Glass Skin 1.01 Oz/30 mL: https://go.shopmy.us/p-56646122 NUMBUZIN | No.9 NAD+ PDRN Glow Boosting Toner: https://go.shopmy.us/p-56646193 Shop more of my favorite products here: https://shopmy.us/chemistconfessions
We take an objective look at two polar opposite formulas—a $20 "junior" product and a $250 luxury serum—to see if the high science matches the high price tag. We break down the mysteries of sourcing, discuss why your 1% active might not be what it seems, and share our honest (and sometimes smelly) trial experiences. Whether you’re looking for genuine rejuvenation or just want to avoid lighting $500 on fire, we’ve got the data you need to navigate this rapidly changing landscape. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions #skincare #skincarescience #pdrnserum #pdrn #salmonpdrn
Chemist Confessions Minis! https://chemistconfessions.com/shop/kits&minis We're pickup where we left off with another science update episode! Today, we're diving into another buzzy ingredient in the "longevity" space: PDRN. In this episode, we go beyond the "salmon sperm" headlines to investigate the latest science update on plant-derived PDRN from peony & rose, discuss the potential impact of molecular weight, and discuss early looks of unique PDRN delivery systems. Let's navigate the complex clinical data behind these DNA fragments and see if they actually match up to the marketing hype. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions #skincare #skincarescience #pdrnserum #pdrn #salmonpdrn
Exosome is that $500 buzzword that's not going anywhere anytime soon. The claims have only gotten broader from healing, skin regeneration, eczema, anti-aging, to even alopecia. In this episode, we provide an update on any new data since our last deep dive last year. We discuss how these tiny lipid nanovesicles—ranging from 30 to 200 nanometers—function as "biological mail" that triggers collagen synthesis and other regenerative pathways. But do the theories really convert to proven topical benefits? We also tackle one of the most important things you should know about exosomes - sourcing. Does it matter if your exosomes come from humans, plants, or bacteria? And what sort of skin benefits could exosomes provide...if any. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions
In this episode, we are diving deep into the retinal (retinaldehyde) landscape to see how current market offerings stack up. Following our technical breakdown of retinol versus retinal, we shift our focus to real-world testing of popular formulations from Krave Beauty, Prequel, Celimax, and Medik8. We examine the scientific validity of concentration ranges—from the entry-level 0.05% to the more intense 0.24%—and discuss how different textures and price points impact the user experience for various skin types. Whether you are a retinoid rookie or a seasoned pro, we provide the detailed assessment on the data to find the right one for your particular skinario. Timestamps: 00:00 - Intro 02:18 - Product Aesthetics & Textures 08:35 - Krave Beauty 24 Retinal Decode 10:21 - Prequel Retinal Renewal Decode 15:48 - Celimax Vita-A Retinal Shot Decode 22:00 - Medik8 Crystal Retinal 6 Decode 23:51 - Is Retinal 11x faster than Retinol? 28:39 - Chemists' Favorite Retinal (Personal favorites and usage recommendations) Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 PREQUEL | Retinal Renew Retinaldehyde Gel: https://go.shopmy.us/p-51236222 CELIMAX | The Vita-A Retinal Shot Tightening Booster: https://go.shopmy.us/p-51236269 KRAVEBEAUTY | 24 Carrot Retinal Gentle 0 05 Retinal Serum: https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions
We are diving back into the "rumor mill" of the retinoid world! Is Retinal actually better than Retinol, or is it just better marketing? In this episode, we revisit the Retinol vs. Retinal debate with new 2026 data. We break down what the evidence says about the retinoid conversion pathway into retinoic acid. We look at the latest clinical evidence to help you decide if it’s time to switch your anti-aging active or stay the course with your current skincare routine. Episode Timestamps 0:00 - Intro: Revisiting the Retinoid Rumor Mill 1:34 - Why Retinal (Retinaldehyde) is Growing in Popularity 2:01 - The Science of Retinoic Acid Conversion Steps 5:30 - What the Data Shows (Retinol vs. Retinal ex vivo Conversion) 9:15 - Retinal vs. Retinol: Potency & Efficacy Realities 14:40 - Is Retinal Actually Gentler? (Irritation & Skin Barrier) 18:20 - Debunking High-Concentration Retinoid Myths 23:55 - Reviewing Recent Retinal Product Launches 28:10 - How to Choose: Retinol or Retinal for your Skin Type? 36:22 - Final Verdict: Should You Switch Your Active? Resources & Mentions Retinal vs Retinol on the CC Blog: https://chemistconfessions.com/blogs/retinal-is-it-better-than-retinol Retinol vs Tretinoin: https://chemistconfessions.com/blogs/tretinoin-vs-retinol Follow us on IG : @chemist.confessions #chemistconfessions #retinal #retinol #skincarescience #antiaging #retinaldehyde #skincareroutine
Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science.The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a skincare routine, finding a serum that’ll ACTUALLY deliver, or just want to have a few laughs on some of the crazy things you see in skincare.
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