
Vanessa Vongsouthi, Research Founder and Head of Bioengineering at Samsara Eco, joins host Erum on the Grow Everything Podcast to discuss how engineered enzymes and AI are unlocking infinite recyclability for textiles and plastics. Vanessa walks through Samsara's process of breaking complex polymers like Nylon 6,6 down into their chemical building blocks using AI-assisted protein design and ancestral sequence reconstruction, then feeding those monomers back into existing supply chains as virgin-equivalent materials — indistinguishable from what's extracted from petrochemicals today. She shares the story behind the world's first enzymatically recycled Nylon 6,6 jacket created in partnership with Lululemon, how Samsara was built using Main Sequence Ventures' orchestration model alongside partners like Woolworths and ANU from day one, and what a future of distributed local recycling infrastructure could mean for designers, manufacturers, and consumers everywhere.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) - Intro: Heat waves, climate impacts, and the bioeconomy(00:03:00) - Would Big Tech buy a pharmaceutical company?(00:08:00) - Brewed human collagen: Gelatech x Hugel partnership(00:10:00) - France bans fast fashion: Shein, Temu, and the Atacama Desert(00:13:00) - Introducing Vanessa Vongsouthi of Samsara Eco(00:17:00) - Biology as future industrial infrastructure(00:22:00) - Programming enzymes with AI and ancestral sequence reconstruction(00:29:00) - The Lululemon jacket: proof that enzymatic recycling scales(00:35:00) - Distributed recycling and a circular material economy(00:42:00) - Post-interview debrief and key takeawaysLinks and Resources:Forbes - Vanessa VongsouthiSamsara EcoSamsara Eco - LinkedInHow Samsara Eco made a jacket with Lululemon from enzymatically recycled polyesterlululemon and Samsara Eco Announce 10-Year Plan to Advance Recycled Material PortfolioThe world has an anchovy problemAI Age Anthropic launches AI drug discovery program, joining tech giants in betting on healthcareFDA to fast-track food as medicineJellatech Partners with South Korea’s Hugel to Bring Cell-Cultured Human Collagen to MarketFrench parliament passes fast fashion bill targeting Shein and Temu149. Beyond Capital: Phil Morle of Main Sequence Ventures on Collaboration as the New Competitive Edge45. Insuring Your Lunch: Aanika’s Vishaal Bhuyan Cracks the Microbial Code of Food Security<a href="https://open.spotify.com/episode/2gjg3arQPkTORhxHStSNCF?si=jPNA4pFYTsyR1DHLEJpA4Q" target="_blank" rel="ugc
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191. Beyond the Lab Bench: Karl & Erum on Human Connections as the Ultimate Biotech Moat

190. Pour Some Sugar on Yeast: Lisa Roessler Scales Biology at Amyris

188. Which Came First: Chicken, Egg, or Medicine? Neion Bio Turns Evolution into a Precision Factory

187. One Small Step for a Microbe: Lynn Rothschild’s Leap from Astrobiology to Bioengineering at NASA
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