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by Steve Hsu
Steve Hsu is Professor of Theoretical Physics and Computational Mathematics, Science, and Engineering at Michigan State University. Join him for wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, investors, and more.
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- 1 weeks ago1h 11m
Effort News and AI-Driven Journalism with Brian Chau – #121
Brian Chau is a mathematician, machine learning specialist, and the founder of Effort News, an independent media outlet focused on data-first, document-led investigative journalism.https://www.effort.news/https://x.com/brianchau57Chapter Markers: - Intro - Network School Fallout - Effort News Origins - AI Reporting Workflow - Medicare Medicaid Momentum - Epstein Files AI Law - Biolabs Base Rates Debate - Business Model And AI Math Finale –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- 3 weeks ago1h 14m
Machine God: Hsu, Greer, Huang – #120
Machine God is a feature-length AI documentary film, created by Steve Hsu, John Greer, and Lei Huang. This episode discusses the film's creation and content.Chapter Markers: - Meet the Filmmakers - Berkeley AI Boomtown Origins - Techno Capital and the Pause Plea - Why Slow Down AI - Recursive Self Improvement - Gradual Disempowerment - Film Release and Closing –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Aug 27, 20261h 0m
How to Build a Research Institute: Thomas Fink of the London Institute for Mathematical Sciences – #119
Dr. Thomas Fink is an Anglo-American physicist, author, and entrepreneur who serves as the founding Director of the London Institute for Mathematical Sciences (LIMS).He studied physics at Caltech, where he won the Fisher Prize, and earned his PhD at Cambridge University. His research focuses on statistical physics, combinatorics, and evolvable systems, using these tools to gain insights into physical and biological systems.In 2011, Dr. Fink founded LIMS, the UK's first independent research centre for theoretical physics and mathematics. Located in the historic Royal Institution in Mayfair, LIMS operates like a university research department but with no teaching or administrative duties, allowing its researchers to focus entirely on full-time, curiosity-driven discovery.London Institute for Mathematical Sciences (LIMS): https://lims.ac.uk/Dr. Thomas Fink's Profile at LIMS: https://lims.ac.uk/thomas-fink/Chapter Markers: - Thomas Fink: Caltech, Cambridge, CNRS Paris - Rethinking Academia - Building LIMS - Saving Basic Science - Endowments Versus Governments - AI Reshaping Research Culture - Closing Thoughts –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Aug 13, 20261h 5m
Venture Capital and Technology in China with Bohan Lou – #118
Bohan Lou is a partner at Chemistry Ventures, based in SF.https://x.com/loubohanBohan's report on the venture ecosystem in China:https://www.linkedin.com/posts/bohanlou_i-spent-last-month-in-china-meeting-most-ugcPost-7487909585689698304-qepw/Chapter Markers: - Venture Capital in China; Bohan’s Shanghai Roots - Chemistry Fund and China Investing - China Trip and Venture Reality Check - Pressure Cooker: Founder Exits and Financial Liability - Variation in Founder-Friendly investment environment - AI Models and Open Source - Big Picture and Wrap Up –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Jul 30, 202652 min
Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast)
This is a crossover episode with Alf Beckinsale, an Oxford University student who hosts the Seeking Truth From Facts podcast. The main topics are the US-Iran conflict, geopolitics, and US-China AI competition.Chapter Markers: - Introduction - No Off Ramp in Gulf - Missile Stockpile Crisis - Oil Shock and Reserves - Israel Stays Out - China Frontier AI Surge - World War and Nukes –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Jul 16, 202651 min
State of AI, Summer 2026 – #116
Steve discusses the state of AI in summer 2026. Topics covered include: AI in math and theoretical physics, Recursive Self-Improvement, Agent swarms and tokenomics, IPOs and US-China competition, documentary film Machine God.Machine God trailer: https://www.youtube.com/watch?v=5RSv3wmDIpYTheoretical Physics with Generative AI: https://stevehsu.substack.com/p/theoretical-physics-with-generativeChapter Markers: - State of AI, Summer 2026 - AI in Math Physics - Recursive Self-Improvement - DeepSeek Hyperconnections - Agent Swarms and Tokenomics - Machine God Documentary –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Jul 2, 20261h 40m
Beff Jezos and Effective Accelerationism: Machine God of Loving Grace
Beff Jezos (Guillaume Verdon) is a Canadian physicist, quantum computing researcher, and tech entrepreneur. He is best known as the founder of the Effective Accelerationism (e/acc) movement.This interview was recorded in collaboration with John Greer and Lei Huang for the documentary film Machine God.John Greer: https://www.johncgreer.com/Chapter Markers: - Meet Beff Jezos - Hyperstition vs AI Doom - Accelerate or Die - Scaling Intelligence Upside - Doomers Power Centralization - EAC Physics Framework - Debating Doom Narratives - Beff Jezos Origin Story - Pause Debate and Rapid Fire –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve. Announcing this for some friends at Mechanize - a startup that builds environments for training and evaluating frontier LLMs. Its customers include the top AI labs, and it has contributed to the breakthrough in coding capabilities of frontier models. Mechanize is hiring! https://mechanize.work/b/hsu Compensation is extremely competitive. For technical roles, $300-500k. They are also seeking smart generalists. For example: Research Engineer, Alignment: Build evals that test for misaligned model behaviors $500K salary Puzzle Maker: Design interesting and original puzzles that LLMs can’t yet solve $300K salary Mechanize understands that my readership is highly selected. There is a VERY GOOD CHANCE you will be interviewed if you apply via the link above.
- Jun 18, 20261h 20m
Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114
This episode was recorded live at Manifest 2026. Razib Khan is a prominent writer, population geneticist, and podcaster. He is best known for his extensive deep-dives into human evolutionary history, consumer genomics, culture, and ancient DNA. https://x.com/razibkhanhttps://x.com/razibkhan?lang=enChapter Markers: - Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia - Manifest Q&A Kickoff - Yamnaya: Ancient DNA Mysteries - Yamnaya: Y Chromosome Conquests - Embryo Screening and AI - Conformity and Tenure - Academia: Reforms - Academia: Ideological Capture and Funding - Controversies and Closing Q&A –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.
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About Manifold
Steve Hsu is Professor of Theoretical Physics and Computational Mathematics, Science, and Engineering at Michigan State University. Join him for wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, investors, and more.
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