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by Max Brennan - Biotech HeadHunter
Welcome to The BioHub, where the doors to the world of biotechnology swing wide open. Join your host, Max Brennan, a seasoned biotech recruiter, as he engages in thought-provoking conversations with the brightest minds in biotech. This podcast is your backstage pass to the insights, strategies, and stories that fuel success in the dynamic and ever-evolving biotech landscape. Get ready for an immersive experience into the world of biotech with The BioHub.
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We welcomed Mandana Honu onto the BioHub podcast
In this episode of The BioHub Podcast, Ben is joined by Dr. Marc Hedrick, President & CEO of Cerenome, and Russell Bradley, President & General Manager of CNSide Diagnostics.We explore why CNS cancers remain so difficult to diagnose and treat, and how Cerenome is attempting to address both sides of that problem.Russell takes us inside CNSide®, the company’s cerebrospinal fluid-based diagnostic platform, including how it differs from traditional cytology, the importance of rare-cell characterisation, and what better diagnostic information could mean for treatment decisions.Marc then discusses REYOBIQ™, Cerenome’s targeted radiotherapeutic platform, the challenge of delivering sufficient therapeutic intensity into the CNS while managing toxicity, and the broader opportunity to connect diagnosis, treatment and longitudinal monitoring.A fascinating conversation at the intersection of diagnostics, therapeutics and precision CNS oncology.
In this episode of The BioHub by Avetix, I’m joined by Dan O’Connell, President and CEO of Acumen Pharmaceuticals.Dan shares his journey from neuroscience investing and company creation into the CEO role, and how he has helped take Acumen from a private, preclinical biotech into a publicly traded clinical-stage company focused on Alzheimer’s disease.We discuss the origins of Acumen, what it was like taking the company public with just nine people, navigating a difficult few years for biotech, balancing financial discipline with clinical progress, and the major readout ahead later this year.
In this episode of The BioHub by Avetix, I’m joined by Paul Hastings, CEO of Nkarta.Paul has spent more than three decades in biotech, leading companies across oncology, rare disease and cell therapy, while also becoming one of the industry’s most prominent patient advocates. At Nkarta, he’s now leading the development of allogeneic NK cell therapies designed to make cell therapy safer, more scalable and more accessible.We discuss the evolution of biotech since Paul entered the industry in 1989, the future of cell therapy, the challenges of scaling access, the US clinical and regulatory environment, the importance of patient advocacy, and the mentors and lessons that have shaped his career.
We welcomed Lei Fang the CEO of Excalipoint to the BioHub
Today we’re joined by Jay Fine, President of Research & Development at EvolveImmune Therapeutics.Jay has spent more than 30 years working across drug discovery and development, with a career spanning immunology, immuno-oncology, inflammatory diseases and respiratory disorders. Before joining EvolveImmune, he spent many years at Boehringer Ingelheim, where he led global research efforts in immunology and respiratory diseases, with his teams playing a key role in advancing therapies including Skyrizi and Spevigo.Earlier in his career, Jay held leadership and research positions at Roche, Schering-Plough and the National Cancer Institute, giving him experience across academia, large pharma and biotech.Today, we’ll talk about Jay’s journey through the field, the lessons he’s learned from taking medicines from discovery into development, his experience building and leading scientific teams, and what he sees as the biggest opportunities and challenges in drug development today.
Editor’s note: At the time of recording, Alan Bash was serving as Interim CEO of Legend Biotech. He has since resumed his role as President of CARVYKTI® following the appointment of Ingrid Zhang as CEO.In this episode of The BioHub by Avetix, I’m joined by Alan Bash, President of CARVYKTI® at Legend Biotech.Alan shares what drew him to Legend, what he believes has made the company such a standout success in cell therapy, and his experience stepping into the Interim CEO role during an important period of transition.We also discuss the journey behind CARVYKTI, the importance of global partnerships, the challenges of manufacturing and scaling cell therapy, and what the next chapter could look like for Legend as it builds beyond its first major commercial success.
Today we’re joined by Dr. Stacy Blain, Founder and CEO of Concarlo Therapeutics.Stacy has spent more than 30 years working in cell cycle and cancer biology, including two decades as a tenured professor and NIH-funded researcher at SUNY Downstate. She then made the transition from academia into entrepreneurship, founding Concarlo to develop new approaches to treating drug-resistant cancers.At Concarlo, Stacy and the team are focused on p27 biology and developing their LOCKTAC approach to target CDK2, CDK4 and CDK6, with an initial focus on drug-resistant breast cancer.Today, we’ll talk about Stacy’s journey from academic scientist to biotech founder, what led her to make that transition, the science behind Concarlo, and what she’s learned from building a company around her own research.
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Welcome to The BioHub, where the doors to the world of biotechnology swing wide open. Join your host, Max Brennan, a seasoned biotech recruiter, as he engages in thought-provoking conversations with the brightest minds in biotech. This podcast is your backstage pass to the insights, strategies, and stories that fuel success in the dynamic and ever-evolving biotech landscape. Get ready for an immersive experience into the world of biotech with The BioHub.
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