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The Beyond Tomorrow Podcast with Julian Issa: Daily Summaries Delivered
by Julian Issa
The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian
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- 2 days ago1h 43m
Ex-DeepMind Scientist WARNS: Why We Still Can’t Trust Today’s AI
Is "AI is dangerous" a warning, or the world's best marketing line?This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at agelessrx.com/beyond-tomorrow.On this episode of Beyond Tomorrow, I sit down with Thore Graepel, co-creator of AlphaGo and former researcher at Google DeepMind. I asked him straight up how close we are to superintelligence, and his answer surprised me: there won't be a single moment we can point to, and he argues human organizations like companies already count as a form of superintelligence. We get into why he thinks "AI will destroy humanity" is the biggest myth in the field, the near-term risks he does take seriously, and why I pushed him on the incentives behind the AI safety messaging coming from the labs.From there we go deep on his core technical argument: that today's transformers are black boxes that mix knowledge and reasoning in the same weights, and that scaling alone will never make them trustworthy. He lays out a different approach built on explicit beliefs, hypotheses and evidence, and I found it one of the clearest explanations of AI transparency I've heard. In the back half, we talk about his time at Altos Labs, why biology is a reality check for the "cure all disease in 10 years" claims, and his cell annealing theory of rejuvenation. Key TakeawaysThore sees AI progress as a "jagged frontier," not a single superintelligence moment, and by his own definition, AGI is already hereHe argues companies and institutions are already a form of superintelligenceHis P(doom) is very low: extraordinary claims require extraordinary evidence, and he doesn't see itAbout Thore GraepelThore Graepel is a computer scientist and AI researcher who recently left Google DeepMind, where he was a co-creator of AlphaGo and worked on multi-agent systems, reasoning and consciousness research. He has also spent time at Altos Labs, applying his machine learning and physics background to cellular rejuvenation, and writes about AI, reasoning and safety on Substack.⏱ Timestamps00:00 Intro00:06 How Close Are We to Superintelligence?01:42 Are Human Organizations Already Superintelligent?02:56 Is Anyone Trying to Destroy Humanity?04:45 Near-Term Risks: Jobs and the Economy08:08 Why the Transition Will Be Hard10:06 Post-AGI Planning and the Case for Positive Futures14:35 Capability vs. Diffusion: The Train Driver Problem16:46 Optimization vs. Game Theory18:53 The Incentives Behind AI Safety Messaging22:26 What Is Thore's P(doom)?23:25 Why Transformers Are Black Boxes29:19 How Do We Build Safer, More Transparent AI?33:01 Separating Knowledge From Reasoning37:39 Safety vs. Capability and the Trust Ceiling39:45 Narrow AI vs. General AI44:02 Do You Believe in God?47:15 Consciousness and Whether LLMs Are Alive51:08 AlphaGo and Move 3758:29 Credit Assignment and Moral Reasoning01:04:31 Who Sets the Moral Guardrails?01:09:37 The AGI Race: US vs. China01:11:53 Longevity and Altos Labs01:16:01 The Biology Reality Check01:23:04 Pockets of Computability and AlphaFold01:26:05 Yamanaka Factors and Cell Annealing01:35:51 Will the Singularity Happen in Your Lifetime?01:36:49 Rapid Fire Questions with Thore01:41:35 Thore's Best Piece of AdviceResources & MentionsAlphaGo and AlphaFold (Google DeepMind)Thinking, Fast and Slow by Daniel KahnemanAltos LabsStephen Wolfram's "pockets of computability"David Deutsch on simulation and the limits of experimentThore's Subst
- 1 weeks ago1h 51m
Dr Mike Israetel: ‘’ALMOST EVERY American Should Be On GLP-1s, Here’s Why!’’
What if vanity was actually the smart way into a longer, healthier life?This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. Their mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at agelessrx.com/beyond-tomorrow.On this episode of Beyond Tomorrow, Dr. Mike Israetel breaks down what's actually happening in his own bloodstream: 5mg/week of tirzepatide year-round, plus retatrutide during fat-loss phases, and why he thinks “GLP-2” is a gray-market marketing term with no basis in real receptor biology. He walks through the non-weight-loss case for these drugs, reduced systemic and neural inflammation, better glucose control, emerging anti-cancer data, and a documented drop in addictive behaviors from gambling to alcohol to cigarettes, before getting honest about the tradeoffs: undernutrition, anhedonia, and a long-term data set that, by his own admission, will never be “complete enough” for some critics.From there the conversation moves into gray-market peptides, why Mike separates his own risk tolerance from what he'd recommend to the public, and why there currently isn't a single peptide he'd recommend for muscle growth despite the demand. The back half covers his real thesis: that appearance, not health, is the most reliable motivator most people actually respond to and that chasing it tends to produce the same outcomes doctors have failed for decades to sell through fear.Key TakeawaysMike takes tirzepatide (Zepbound/Mounjaro) year-round at 5mg/week and adds retatrutide during cutting phases, both well within studied dose rangesHe argues most GLP-1 “anhedonia” is caloric-deficit anhedonia, not a direct drug effect, the same thing bodybuilders experience on any aggressive dietNew aggregate mortality data shows older adults on GLP-1s die less than those who aren't, which he says partially answers the “but will it kill you later” questionThere is currently no peptide he'd recommend for muscle growth, a claim he says consistently disappoints people who askHis core argument: use appearance as the entry point (build muscle, lose fat, sleep better) and let the longevity benefits follow, rather than trying to motivate people with 30-years-out health outcomesTimestamps00:00 Intro00:10 Is GLP-1 a Bad Idea?08:55 The Seatbelt Analogy for Drugs10:30 The Peptide That's Not FDA-Approved Yet11:30 Exactly What Mike Takes Every Week13:59 Stacking Peptides: an N-of-1 Experiment15:11 Why Mike Takes Anabolic Steroids16:42 The Drug That Could Replace Steroids18:48 Why Mike Takes Tirzepatide and Retatrutide21:45 20-Year Life Extension25:34 Mike's Full Daily Stack30:47 The Looksmaxxing Trojan Horse35:35 Sick Care vs. Health Care38:14 Three Exercises You Can Do Today40:36 Critiquing Brian Johnson's Protocol43:31 Is There a One-Size-Fits-All Workout?46:06 Zone 2 vs. Zone 5 Training52:21 Why Most Biohacking Is a Waste of Money54:01 Is HIIT Still the Rage?57:09 Escaping Poverty, Fueling Success01:04:53 Why People Take Extreme Measures to Look Good01:08:24 Moving Past GLP-101:14:52 Everyone Will Look 22 by 203701:18:24 Would You Date a 90-Year-Old?01:24:52 Beauty Standards in a Post-GLP-1 World01:25:37 The Cybernetic Revolution01:28:25 Living Forever in a Robot Body01:36:29 Will AI Cause Human Extinction?01:43:28 The Biggest Myth About Weight Loss01:44:02 Rapid Fire Questions with Mike01:48:06 Mike's Best Piece of AdviceConnect with Mike: Website: rpstrength.com/ Facebook: facebook.com/michael.israetelInstagram: @drmikeisraetelX: @misraetelConnect with JulianInstagram: @thebeyondtomorrowpodcast / @juliankissaLinkedIn: julian-issaX: @juliankissaWebsite: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com
- 2 weeks ago1h 2m
AI Safety Expert Roman Yampolskiy WARNS About the TWO Likely Endings with AI
What happens when the technology we build becomes smarter than the people who built it?This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrowAI safety researcher Roman Yampolskiy argues the real danger isn't AI, it's building a superintelligence we can no longer control. His case: solve problems with narrow, powerful tools instead, and still get breakthroughs in medicine, science, and productivity, without that risk.The conversation covers AGI, recursive self-improvement, the singularity, and the existential and "suffering" risks they raise, plus what mass automation could mean for work and purpose.From international AI agreements to human longevity, one question runs through it all: can we get the benefits of advanced AI without losing control of it? Yampolskiy's answer: keep building tools, not our replacement.Roman Yampolskiy is an AI safety researcher and professor who studies the risks and implications of artificial intelligence. His work focuses on the challenge of controlling increasingly capable AI systems and the potential consequences of superintelligence.Roman’s book, AI: Unexplainable, Unpredictable, Uncontrollable, explores the various reasons why the field is so challenging.⏱ Timestamps00:00 Intro00:43 Can We Build AI By Design to Avoid Catastrophe?01:49 AI Superintelligence Is a Death Sentence03:12 What Is AGI, Really?04:26 OpenAI's Plan to Build an Internal AGI04:59 Why Superintelligence Won't Care About Us06:45 We're Going to Die Anyway... So What?07:06 We Can't Control Something This Advanced07:55 The Narrow Tools That Avoid AGI09:34 The US vs China AI Race10:47 Does China Actually Want to Stop AGI?11:53 AGI Is a Spectrum, Not a Switch12:22 Is Roman Selling the Doom Narrative?14:13 How to Stop AGI From Escaping the Box16:26 Building AI We Can't Control18:05 Suffering Risks: The Worst-Case Scenario20:09 The Two Types of Jobs22:09 What Happens to the 90% Who Lose Their Jobs?23:46 Nothing Makes AI Labs Stop24:26 Building Something You Can't Control26:06 Do You Believe in God?29:28 Longevity Escape Velocity Without AGI30:55 Is Suffering Necessary for the Human Story?31:33 Are We Living in a Simulation?32:12 You Can't Control Superintelligence33:24 Is Our Life a Simulation?35:05 Curing Aging With Narrow AI Tools36:10 What Is an NPC?36:37 Could Humans Cause Doom Before AI Does?37:21 How to Break Out of a Simulation39:14 Would You Live Forever in a Simulation?40:01 Don't Build Superintelligence41:50 Bostrom's Singleton Theory43:17 "AI Is Massively Overhyped"44:56 Would AI Doom Be Worse Than World War 3?45:41 Who Should You Actually Be Listening To?47:43 What Would a Perfect Simulation Look Like?50:52 Solving Longevity Without AI52:03 Our Limited Understanding of Human Biology52:40 What Makes Roman Happy?53:48 Signs Governments Are Waking Up55:14 "Is AI Just a Con?"56:53 Can Squirrels Control Humans?58:27 Decide What to Do With Your Time59:22 What About Ilya Sutskever?01:00:13 The Responsible Use of Technology01:00:46 If Tomorrow is Your Last Day...Connect with Roman: Website: https://www.romanyampolskiy.com/ Facebook: https://www.facebook.com/roman.yampolskiy/ LinkedIn: https://www.linkedin.com/in/romanyam/ X: https://x.com/romanyam Connect with JulianInstagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa
- 2 weeks ago8 min
BT Clip: Longevity Experts: The Tipping Point That Will Trigger a Global “War on Aging” (Matt Kaeberlein, Aubrey de Grey, and Gordan Lauc)
Let's get into the rapidly evolving future of longevity, from the moment society finally believes aging is solvable to the possibility of humans routinely living far beyond today’s lifespan — even approaching 150 years. Matt Kaeberlein, Aubrey de Grey, and Gordan Lauc explore how breakthroughs in aging science could also extend the lives of companion animals, while exposing how bad science and misallocated resources continue to slow meaningful progress. It’s a grounded, forward-looking discussion on what true longevity innovation requires.Watch the full episode here: https://open.spotify.com/episode/1Rmtl7sqoFOWolXWV6O22U?si=cd176f6a28404b4d
- 3 weeks ago45 min
DAVID EAGLEMAN: The END of Human Presidents is COMING. Should We Worry?
Could an AI actually run the country better than a person could?This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrowDavid Eagleman doesn't shy away from the question. He lays out the case for an AI president, one that could crunch more data than any human cabinet, sidestep the ego and grudges that shape so many political decisions, and maybe even out-think our worst instincts.Sounds great, until you ask the harder questions. Who writes the code that decides what "the greater good" means? Can a machine actually be moral, or just really good at faking it? And if an AI ever did hold real power, who's holding the leash?We get into all of it: democracy, tribalism, consciousness, and how close we actually are to AGI. David doesn't pretend to have it all figured out but he makes a compelling case that the ground is shifting faster than most of us realize.David Eagleman is a neuroscientist at Stanford University and an internationally bestselling author. He is co-founder of several neurotech companies, including Jojo, BrainCheck, and Neosensory, and he also directs the Center for Science and Law, a national non-profit institute. He is best known for his work on sensory substitution, time perception, brain plasticity, synesthesia, and neurolaw.⏱ Timestamps00:00 Intro00:05 Are We in the Middle of AGI?03:26 AI’s Greatest Advantage04:25 The Case for a Utilitarian AI President07:16 Who Defines AI’s Parameters?09:06 The Danger of Politically Biased AI11:49 Behind the Scenes12:33 Are We Ready for an AI President?14:41 What Should an AI Government Optimize For?18:31 How Soon Could We Have an AI President?22:24 The Trolley Problem and AI Morality27:54 What Happens When Humans Have Too Much Free Time?29:07 The Neuroscience of Tribalism30:13 The Neural Basis of Empathy31:24 Why We’re Wired for Us vs. Them32:43 Can AI Become Conscious?33:51 Could AI Eradicate Humanity?35:51 Artificial Wisdom and AI Guardrails38:57 AGI Is Already Happening41:22 An AI President in Our Lifetime43:26 The Biggest Fear About AIConnect with David: Website: https://eagleman.com/ Facebook: https://www.facebook.com/David.M.Eagleman LinkedIn: https://www.linkedin.com/in/davideagleman/ Instagram: https://www.instagram.com/davideagleman X: https://x.com/davideagleman TikTok: https://www.tiktok.com/@drdavideagleman Connect with JulianInstagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: <a href="http://www.beyondtomorrowpodcast.com" rel="ugc noop
- 3 weeks ago7 min
BT Clip: Harvard Geneticist: "Immortality May Have Already Happened!" (George Church)
What if immortality didn’t arrive as a single breakthrough but quietly, step by step?In this clip, George Church explains the idea of “longevity escape velocity”: the point where medical progress extends life faster than we age. If each generation of therapies buys us more time to develop the next, the path to dramatically longer lives or even practical immortality may already have begun.Watch the full episode here: https://open.spotify.com/episode/0c2x5fNYLSzvvfIil3c7WK?si=854bb724225e4136
- Sep 3, 202614 min
Peter Diamandis: "AGI Is Already Here - They Just Haven't Released It Yet"
What if the Singularity isn’t coming but already here?This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrowAI is accelerating breakthroughs across science, medicine, and technology at a pace once considered impossible. Peter Diamandis believes the next 5–10 years could redefine what humanity can achieve.Yet AI’s promise is competing with fear, disruption, and dystopian narratives. The challenge is not only building the future, but shaping how people imagine it.For Peter Diamandis, the answer is actionable optimism: identify the risks, believe they can be solved, and pursue the biggest moonshots. Longevity, education, and space could become the foundations of a radically different future.Peter Diamandis is an entrepreneur, physician, and founder of XPRIZE and Singularity University. He is a leading advocate for moonshot thinking and breakthrough technologies.⏱ Timestamps00:00 Intro00:10 The Blinding Speed of Change02:06 A Future Where Anything Is Possible04:06 Why Is the West Afraid of AI?08:39 Why Fear AI?10:23 AGI Is Already Here11:37 Blind Optimism vs. Actionable Optimism13:01 The Next Great Moonshot14:01 The Rise of an Alien-Looking Economy15:10 Who Will Win the XPRIZE?15:46 If Tomorrow Was Your Last Day...Connect with Peter: Website: https://www.diamandis.com/ Facebook: https://www.facebook.com/PeterDiamandis/LinkedIn: https://www.linkedin.com/in/peterdiamandis/Instagram: https://www.instagram.com/peterdiamandisX: https://x.com/peterdiamandisYouTube: https://www.youtube.com/@peterdiamandis Connect with JulianInstagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.
- Sep 1, 20269 min
BT Clip: AGI Pioneers: ChatGPT Won’t Get Us to AGI.. Here’s What Will (Ben Goertzel)
Are large language models like ChatGPT and Claude enough to create AGI?In this clip, Ben Goertzel explains why today’s LLMs are incredibly powerful, but still fundamentally different from true artificial general intelligence.He argues that simply building a bigger version of ChatGPT or Claude is unlikely to produce human-level AGI. Instead, reaching AGI will require new AI architectures that can go beyond their training, generalize to unfamiliar problems and make genuinely novel leaps in reasoning.Ben also explains why current models can already outperform humans in areas like coding, mathematics and knowledge retrieval, while still struggling with the kind of imagination and general intelligence humans use to push beyond existing knowledge.Full episode here: https://open.spotify.com/episode/7wGN1x0vQQgdzoktHipqBK?si=454702357d55415e
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About The Beyond Tomorrow Podcast with Julian Issa
The future feels exciting but a little scary. We're here to help guide you through it. How? 1. Building stronger, more abundant mindsets. 2. Shining a spotlight on the technologies of tomorrow. 3. Identifying the latest longevity & health protocols. Health, longevity, human potential and AI. It's great to have you here. Julian
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