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The Dr. Hyman Show: Daily Summaries Delivered
by Dr. Mark Hyman
Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity. In a world where our food system fuels disease and conventional healthcare often overlooks root causes, Dr. Hyman delivers evidence-based insights and expert conversations that empower you to become the CEO of your own health. The Dr. Hyman Show goes beyond the headlines to envision a future where our food and healthcare systems support vitality, reduce chronic disease, and protect the environment. Whether you’re looking for actionable protocols, deeper understanding, or meaningful conversations at the intersection of health, food, and policy, this podcast is your trusted guide.
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- Today1h 19m
Undiagnosed Infections Are Silently Causing Chronic Disease | Dr. Richard Horowitz
Living with chronic illness can feel like collecting diagnoses without getting real answers. Symptoms are treated one at a time, but the underlying causes can easily be missed. What if asking a different question is the first step toward feeling better? In this episode, I’m joined by Dr. Richard Horowitz, an internationally recognized Lyme disease expert and author of the new book Ending Chronic Illness. After caring for thousands of patients over more than four decades, he explains why many seemingly unrelated conditions share common underlying drivers—and why thinking like a medical detective may help uncover them. We discuss: Why treating the diagnosis isn't always the same as treating the problem—and how to start looking deeper How hidden infections, environmental toxins, gut health, and other overlooked factors can quietly drive chronic illness What new research may reveal about the links between infection, inflammation, and brain health How to begin uncovering what's really driving persistent symptoms Our bodies are constantly communicating with us. The challenge isn't that they're silent—it's that we haven't always known how to listen. Sometimes finding better answers begins with asking different questions. Continue Exploring If you'd like to explore Dr. Horowitz's work further, here are two great places to start: Take his Symptom Assessment Quiz to better understand what may be contributing to your symptoms. Subscribe to his Medical Detective Substack ****for ongoing insights into chronic illness, Lyme disease, and root-cause medicine. Interested in getting tested? Many of the lab tests discussed in this episode are available through Function, making it easier to get a more comprehensive picture of your health. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Cozy Earth, Seatopia, Perfect Amino, BON CHARGE, and Made In. Support healthy aging and get up to 20% off when you subscribe on top of the new starting price of $79 at timeline.com/drhyman. Upgrade your sleep setup with cozyearth.com and enjoy 20% off with code HYMAN. Find a cleaner source of seafood. Check out seatopia.fish and use code HYMAN for free shipping on your first order. Help fill protein gaps at bodyhealth.com and use code HYMAN20 for 20% off. Explore red light products at boncharge.com/hyman and enjoy 15% off with code HYMAN. Explore kitchen essentials at madeincookware.com and save 10% off your first order with code HYMAN-HIVE. Infections and toxins as root causes of chronic illness; Dr. Horowitz's background and journey to functional medicine Discovering and treating various infections, toxins, and Dr. Hyman's personal health story Root causes of chronic disease, inflammation, and testing for infections and toxins Sponsor: Seatopia and PerfectAmino Importance of diet, addressing multiple health factors, and autoimmune misdiagnosis Role of infections, toxins, microbiome, and leaky gut in autoimmune diseases and inflammation Treating underlying causes and neuroinflammation in chronic diseases Nutritional deficiencies, COVID-19, and the importance of sleep in chronic illness management Plant medicines, supplements, and dapsone in treating neuroinflammation, Lyme, and Alzheimer's Use of methylene blue in treatment protocols Sponsor: Bon Charge Sponsor: Made In Evolution of treatment protocols and six principal causes of inflammation Importance of adrenal function and hormone treatment in chronic illness Differential diagnosis vs. root cause analysis and root cause testing Horowitz's questionnaire and protocols for treating chronic infections Addressing mold-related health issues and Dr. Hyman's personal experience Mold testing, detoxification, and controversies in treatment Insurance challenges and HHS innovation grant for chronic illness research Importance of root cause medicine and Mark Hyman's upcoming book on longevity Personalized medicine, reversing Alzheimer's biomarkers, and research fun
- 2 days ago26 min
Lyme Disease: The Symptoms, Tests, and Treatments Doctors Miss
What if the fatigue, brain fog, joint pain, or mysterious symptoms you've been chasing for years weren't caused by stress, aging, or burnout—but by a tick bite you never even noticed? Lyme disease is one of the most misunderstood illnesses in medicine. But Lyme is rarely just one infection—it's often part of a much bigger picture involving co-infections, immune dysfunction, inflammation, gut health, and environmental triggers. In today's episode, I walk through a functional medicine approach to Lyme disease and tick-borne illness, including: Why Lyme disease is so often missed—and the hidden role of co-infections like Babesia, Bartonella, Ehrlichia, and Anaplasma The limitations of conventional testing and treatment, and how functional medicine looks beyond the infection to understand why some people recover while others remain chronically ill The role of herbs, antibiotics, gut repair, detoxification, immune support, and mitochondrial health in a comprehensive recovery plan What the latest evidence says about emerging therapies like ozone, hyperbaric oxygen therapy, and hyperthermia—as well as practical strategies to prevent tick-borne illness in the first place Lyme disease isn't always just an infection—it's often a whole-body disruption. By addressing the underlying drivers of inflammation, immune dysfunction, gut health, and cellular resilience alongside the infection itself, you give your body the best chance to heal and recover. Resources Mentioned: Track your metabolic health with Function Health: https://functionhealth.com/mark (Use code MARK2026 for $50 off your membership.) Have a question you’d love answered on Office Hours? Submit it here Introduction to Lyme disease, overview, and Dr. Hyman's experience Functional medicine's approach and comprehensive treatment strategies Innovative therapies for Lyme disease Managing die-off reactions and restoring gut health Supporting the immune and nervous systems; prevention strategies Future research, persistent symptoms, and conclusion Alzheimer's disease, neuroinflammation, and call to action
- 1 weeks ago1h 1m
Big Pharma's Trillion Dollar Deception on Mental Health | Joanna Moncrief
For decades, depression has often been described as the result of a chemical imbalance in the brain. But how strong is the evidence behind that idea? This episode explores one perspective on an area of medicine that continues to be actively debated and is intended to encourage thoughtful discussion—not to provide individualized medical advice. Today on The Dr. Hyman Show, I'm joined by psychiatrist and researcher Dr. Joanna Moncrieff to examine the science behind the serotonin theory and explore how it shaped modern mental health care. Together, we consider why rethinking our assumptions may open the door to a more complete understanding of depression and recovery. We discuss: • Whether depression is best understood through the lens of a chemical imbalance—or something far more complex • How the serotonin theory shaped modern psychiatry and why it's increasingly being questioned • What current research says about antidepressants, emotional numbing, and informed consent • Why lifestyle, nutrition, trauma, and social connection deserve a larger role in supporting mental health • How a more individualized, whole-person approach could change the way we think about depression and recovery Mental health treatment is deeply personal, and this episode explores one perspective on an area of medicine that continues to evolve. If you're currently taking antidepressants or other prescription medications, don't stop or change your treatment based on this discussion alone. Instead, use it as a starting point for an informed conversation with your healthcare provider. Learn More: Dr. Moncrieff recently participated in an FDA Expert Panel on SSRIs and Pregnancy. If you'd like to explore another perspective on the evidence discussed in this episode, you can watch the panel here. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by BIOptimizers, fatty15, Rho, Paleovalley, Pique, and Big Bold Health. Go to bioptimizers.com/hyman and use code HYMAN to save 15% off your order, plus get a free gift. Head to fatty15.com/hyman today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Explore science-backed products at rhonutrition.com and use code HYMAN for 20% off the entire site. Shop nutrient-rich foods and supplements at paleovalley.com/hyman and save 15% off your first order. Elevate your daily wellness ritual at piquelife.com/hyman and enjoy 20% off plus free gifts. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. The impact of the chemical imbalance theory and myths of mental illness Disclaimers and introduction of Joanna Moncrieff The serotonin myth, antidepressant use, and marketing of SSRIs Risks, side effects, and wrong-headed approaches to mental health Societal, biological, and lifestyle factors in mental health Commercial determinants of health The rise and implications of psychedelic treatments in psychiatry Drug-centered vs. disease-centered models in mental health The role of the brain and alternative approaches to treating depression Addressing severe depression and strategies for deprescribing antidepressants Reframing mental health narratives and future outlook Encouraging self-education, debate, and discussion in medicine Closing remarks, disclaimers, and gratitude to sponsors
- 1 weeks ago18 min
3pm Slump Destroying Your Focus? Here's What's Really Happening
Do you hit a wall every afternoon around 2 or 3 p.m.? If your energy disappears, your brain gets foggy, and you need caffeine or sugar just to finish the day, it isn't a lack of willpower—it's a sign that something deeper is driving your energy crash. In this episode, I explain the three biggest drivers of the afternoon slump and the simple changes that can help you maintain steady energy all day long. In today's episode, I discuss: The three hidden causes of the afternoon energy crash Why skipping breakfast, relying on coffee, sugary smoothies, or carb-heavy meals sets you up for an inevitable drop in energy later in the day How to build meals with protein, healthy fats, and fiber to stabilize blood sugar and create lasting energy instead of quick spikes and crashes Simple daily habits that can dramatically improve your energy and focus That afternoon crash isn't something you have to accept as part of modern life. When you stabilize your blood sugar, support your body's natural rhythms, and reduce chronic stress, your energy becomes more consistent, your focus improves, and you stop relying on caffeine and willpower just to make it through the day. Resources Mentioned: Track your metabolic health with Function Health: https://functionhealth.com/mark (Use code MARK2026 for $50 off your membership.) Have a question you’d love answered on Office Hours? Submit it here Understanding the afternoon crash and blood sugar's role in energy Importance of circadian rhythm Environmental toxins and health Impact of stress on energy and caffeine use Rapid fire Q&A Key takeaways for steady energy
- 2 weeks ago1h 7m
Heart Rate Variability | Why Your Nervous System Needs This.
We all experience stress. The real challenge isn't stress itself—it's whether we recover from it. Over time, chronic stress can quietly affect everything from inflammation and metabolism to sleep, digestion, and healthy aging. This week on The Dr. Hyman Show, I talk with nervous system educator and HRV expert Salim Najjar to explore what heart rate variability (HRV) can reveal about your body's ability to recover from stress and build resilience. Together, we unpack: • How to use HRV to better understand your body's response to stress • Why some stress makes you stronger while chronic stress wears you down • How to get more value from your wearable without obsessing over the numbers • Five daily habits that can help your nervous system recover and become more resilient • How your nervous system influences inflammation, healing, and healthy aging Our bodies are constantly responding to the demands we place on them every day. The good news is that resilience can be built, and the strategies in this conversation can help you recover from stress more effectively and support long-term health. To help you get started, Salim has created a free HRV guide that includes a personalized quiz and AI coach exclusively for listeners.View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=linkGet Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastJoin the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Perfect Amino, Cozy Earth, Timeline, Sunlighten, Made In, and Seatopia. Get daily protein support at bodyhealth.com and use code HYMAN20 for 20% off. Head over to cozyearth.com to save 20% and upgrade all of your daily essentials today. Support healthy aging and get 20% at timeline.com/drhyman with code HYMAN. Discover why so many people are using sunlighten.com and use code HYMAN to save up to $2,100 today with free shipping. Upgrade your cookware at madeincookware.com and save 10% off your first order with code HYMAN-HIVE. Find a cleaner source of seafood. Check out seatopia.fish and receive free shipping on your first order. Introduction to HRV Introduction to Salim and his HRV expertise What is HRV and how is it measured Chronic stress, stress regulation, and sovereignty Why HRV is an important health metric Deeper dive into HRV as a health indicator Salim's HRV coaching, website, and personal journey Salim’s framework and steps for improving HRV The role of sleep and hormetic stress in HRV Tools and tracking for HRV measurement The art framework and five pathways for HRV Salim’s injury, reframing, and HRV improvement Viktor Frankl, intentionality, and alignment Community and its role in health and HRV Practical steps for building community and emotional regulation Emotional processing, elite athletes, and HRV performance Sovereignty, compassion, and daily nervous system practices Awareness, parasympathetic activation, and reframing HRV Closing remarks, social media, and gratitude Disclaimer and sponsor acknowledgments
- 2 weeks ago19 min
Too Much Histamine Is Wrecking Your Body — And Most Doctors Don't Know It
Histamine isn't just about seasonal allergies or a runny nose. It influences your brain, gut, hormones, immune system, and nervous system—and when your body can't regulate it properly, it can show up as everything from anxiety and migraines to insomnia, digestive issues, skin rashes, and brain fog. In this episode, I explain why histamine overload happens, how it relates to Mast Cell Activation Syndrome (MCAS), and what a root-cause approach looks like for calming an overactive immune system. In today's episode, I discuss: * Why MCAS and histamine intolerance are different—and how overactive mast cells can drive symptoms ranging from migraines and anxiety to digestive issues, hives, and heart palpitations * The hidden triggers behind mast cell activation, including gut dysfunction, chronic infections, mold exposure, hormone imbalances, stress, and environmental toxins * Why many "healthy" foods like avocados, spinach, tomatoes, kombucha, and bone broth can temporarily worsen symptoms when your histamine bucket is already full * A root-cause approach to calming the immune system using nutrition, targeted supplements, medications when needed, nervous system regulation, and addressing the underlying drivers of inflammation MCAS isn't simply a histamine problem—it's a sign that your immune system has become dysregulated. Instead of just suppressing symptoms, the goal is to understand why your mast cells are overreacting in the first place. When you lower the overall inflammatory load and restore balance to the gut, immune system, hormones, and nervous system, you create the conditions for lasting healing rather than temporary symptom relief. Resources Mentioned: * Track your biomarkers with Function Health: https://functionhealth.com/mark (Use code MARK2026 for $50 off your membership.) * Have a question you’d love answered on Office Hours? Submit it here
- 3 weeks ago51 min
How Brain Inflammation Drives Depression, Alzheimer's, and Parkinson's
For decades, we've thought about conditions like Alzheimer's disease, depression, and Parkinson's disease as disorders of the brain. But what if that's only part of the story? Emerging science is revealing that many of the factors driving cognitive decline, mental illness, and neurodegenerative disease may begin far outside the brain itself—in our metabolism, our immune system, our gut microbiome, our hormones, and even the environment we're exposed to every day. As part of our summer series, we're revisiting some of the most important conversations we've had on the topic of brain health. In this special compilation episode, you'll hear from leading experts Dr. Richard Isaacson, Dr. Chris Palmer, and Drs. Ray Dorsey and Michael Okun as they explore the new science of brain health and what it means for preventing cognitive decline, supporting mental health, and protecting our brains as we age. What I find most encouraging about this research is that it challenges the idea that brain decline is simply an inevitable part of aging. Instead, it suggests that many of the biggest drivers of brain health are things we can influence through the choices we make, the environments we create, and the ways we care for our bodies long before symptoms ever appear. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Sunlighten, Seed, BIOptimzers, Paleovalley, and Pique. Support healthy aging and get 20% off at timeline.com/drhyman with code HYMAN. Discover why so many people are using sunlighten.com and save up to $2,100 today and free shipping with code HYMAN. Make your microbiome part of your daily routine with seed.com/hyman and save 25% with code 25HYMAN. Go to bioptimizers.com/hyman and use code HYMAN to save 15% off your order, plus get a free gift. Shop nutrient-rich foods and supplements at paleovalley.com/hyman and save 15% off your first order. Elevate your daily wellness ritual at piquelife.com/hyman and enjoy 15% off for life plus free gift Understanding brain dysfunction, inflammation, and lifestyle interventions Heavy metals, toxins, and Parkinson's disease Introduction to the summer series on brain health The MIND diet, precision nutrition, and brain-healthy fats Vitamins, supplements, and caloric intake for cognitive health Vitamin D, B complex, and reversing mild cognitive impairment Additional supplements and intensive lifestyle interventions Importance of magnesium and metabolic health Multimodal treatments, hormone replacement therapy, and individualized care Biopsychosocial factors, stress, and the gut-brain connection Inflammation, energy dysregulation, and metabolism in brain health Parkinson's disease: causes, history, and environmental factors Leaky brain, blood-brain barrier, and Parkinson's as a whole-body disease Closing remarks, disclaimer, and gratitude to sponsors
- 3 weeks ago20 min
Your Nervous System Controls Your Gut, Hormones, and Weight — Here's How to Fix It
You've cleaned up your diet. You're taking the supplements. You're exercising, sleeping more, and doing everything "right." So why do you still feel exhausted, inflamed, anxious, or stuck? In this encore episode—one of the most impactful Office Hours conversations we've shared—I explore a question that could change the way you think about healing: What if your nervous system is the missing piece? When your body doesn't feel safe, it prioritizes survival over repair, affecting everything from your metabolism and hormones to your gut, immune system, and brain. In today's episode, I break down: Why chronic stress changes your biology—and how nervous system dysregulation can drive inflammation, hormone imbalance, digestive issues, weight gain, and autoimmune disease The difference between living in constant "fight-or-flight" versus a regulated nervous system that supports healing, resilience, and recovery Simple, science-backed strategies to regulate your nervous system, including breathwork, blood sugar balance, strength training, sleep, and daily safety cues Why you can't out-supplement or out-biohack chronic stress—and how creating physiological safety unlocks your body's natural ability to heal Healing isn't just about finding the right supplement or following the perfect diet. It's about creating an environment where your body feels safe enough to repair itself. When you begin working with your nervous system instead of against it, everything else—from your energy and metabolism to your mood and resilience—can start to change. Check out my full conversation with Dr. Scott Sherr HERE. Track your health with Function Health: https://functionhealth.com/mark (Use code MARK2026 for $50 off your membership.) Have a question you’d love answered on Office Hours? Submit it here Resources Mentioned: Listen to my full conversation with Dr. Scott Sherr on nervous system regulation and mitochondrial health.
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About The Dr. Hyman Show
Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity. In a world where our food system fuels disease and conventional healthcare often overlooks root causes, Dr. Hyman delivers evidence-based insights and expert conversations that empower you to become the CEO of your own health. The Dr. Hyman Show goes beyond the headlines to envision a future where our food and healthcare systems support vitality, reduce chronic disease, and protect the environment. Whether you’re looking for actionable protocols, deeper understanding, or meaningful conversations at the intersection of health, food, and policy, this podcast is your trusted guide.
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