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The Holistic GLP-1 Podcast with Elizabeth McGann: Daily Summaries Delivered
by Elizabeth McGann
Stop doing GLP-1s wrong. Discover how to microdose, release weight and actually heal your body — on the world's #1-ranked podcast for holistic GLP-1 weight loss. Elizabeth McGann, holistic nutritionist, life coach, and microdosing GLP-1 user, shows women how to reach their happy weight, balance hormones and get their sexy back by activating their body's own GLP-1, often with less medication, or none at all. This isn't just weight loss. It's a full-life reboot! Through her signature program, Finally F*cking Free™, group and 1:1 coaching, she teaches The Holistic GLP-1 Method™ "where metabolic science meets intuition, and weight release becomes freedom in every dimension.
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- 3 days ago53 min
The Sustainable Way to Do GLP-1s (with Melissa Mitri)
Millions of women are discovering the benefits of GLP-1 medications, but lasting results require more than simply eating less.In this episode, Elizabeth welcomes registered dietitian Melissa Mitri, who has spent nearly two decades helping clients achieve sustainable weight loss through evidence-based nutrition and lifestyle strategies. Melissa explains why GLP-1 medications work best when paired with healthy habits, proper nourishment, exercise and a long-term mindset.Together, they explore how to naturally stimulate the body's own GLP-1 production, build a foundation for success before starting the medication, preserve muscle and metabolic health during weight loss, and successfully transition off GLP-1s when the time comes.***SHOW NOTES[ 00:00 ] Introduction[ 02:17 ] Preparing for a GLP-1 journey[ 04:00 ] What "nutrient-dense" really means[ 06:08 ] Fiber, satiety, and metabolic health[ 07:18 ] Building sustainable habits[ 08:46 ] The hidden risks of skipping meals[ 12:42 ] Meal prep for real life[ 15:25 ] Naturally stimulating your body's own GLP-1[ 17:26 ] Foods that naturally increase GLP-1[ 19:16 ] Supplements that may help[ 22:43 ] The new GLP-1 pill formulations[ 28:00 ] Personalized medicine and the future of obesity treatment[ 29:24 ] Hunger isn't the enemy[ 31:10 ] Transitioning off GLP-1 medications[ 40:09 ] The mindset component[ 43:08 ] Managing food noise after GLP-1s[ 45:46 ] Exercise and long-term weight maintenance[ 48:38 ] The future of GLP-1s\[ 50:03 ] Melissa's work and resources***Get Connected with Elizabeth McGann:Coaching Website: http://www.ElizabethMcGann.comInstagram: http://www.instagram.com/elizabethmcgannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/elizabethmcgannX/Twitter: https://twitter.com/ElizabethMcGann***Learn more about Melissa MitriInstagram: @the.weightloss.dietitianWebsite: https://melissamitri.com/
- 2 weeks ago8 min
GLP-1s and the Freedom Nobody's Talking About
In this solo episode, Elizabeth explores what most people are missing about GLP-1s.While these medications are often viewed as tools for appetite suppression and weight loss, Elizabeth shares a deeper perspective: how when approached holistically, GLP-1s can create something far more powerful—freedom. Freedom from food noise, from the mental and emotional weight of the struggle, and from patterns that have consumed space for years.As that noise begins to quiet, something new emerges: space.Elizabeth dives into what becomes possible within that space, reframing transformation as more than weight loss—it’s a shift into an entirely new way of being. She also introduces the concept of primary vs. secondary nourishment and why this moment with GLP-1s may offer a profound opportunity for real, lasting change.Because the goal isn’t just weight loss—it’s a life that finally feels like your own.***Get Connected with Elizabeth McGann:Coaching Website: http://www.ElizabethMcGann.comInstagram: http://www.instagram.com/elizabethmcgannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/elizabethmcgannX/Twitter: https://twitter.com/ElizabethMcGann
- May 5, 20261h 13m
GLP-1s Are Not Enough: Eat, Train & Protect Your Metabolism (with Dr. Mike Israetel)
In this episode, I’m joined by Dr. Mike Israetel—PhD in sports physiology, bodybuilder, and one of the most respected voices in muscle, metabolism and body composition. If you’re using (or considering) a GLP-1, this conversation could completely change how you approach your results.We get into what most people are missing: why GLP-1s alone aren’t enough—and how the real magic happens when you combine them with the right nutrition and strength training. Dr. Mike breaks down how you can lose fat without losing muscle (and even build muscle) with just two short workouts a week, why intermittent fasting can backfire, and what’s actually happening when these medications “stop working.”We also talk about bone health, protein intake, side effects, and the future of next-generation GLP-1s.This is one of those episodes that brings clarity, cuts through the noise, and gives you a smarter, more empowered way to do this right.***SHOW NOTES[ 00:00 ] Welcome + Why This Episode Matters[ 04:00 ] The Biggest GLP-1 Mistake Almost Everyone Is Making[ 08:00 ] The Muscle Myth: Why Weight Loss Without Strength Training Backfires[ 12:00 ] The 2x20-Minute Workout That Changes Everything[ 16:00 ] Gym Intimidation: How to Start (Even If You’ve Never Lifted)[ 20:00 ] Yoga, Pilates & Walking: Are They Enough?[ 24:00 ] The Truth About Bone Loss on GLP-1s[ 28:00 ] The Ideal GLP-1 Nutrition Strategy (That Most People Miss)[ 32:00 ] Intermittent Fasting on GLP-1s: Helpful or Harmful?[ 36:00 ] Hitting Your Protein Goals (Even If You’re Busy or Plant-Based)[ 40:00 ] GLP-1 “Tolerance”: Are the Drugs Stopping Working?[ 44:00 ] Dosing Strategy: Why “Start Low, Go Slow” Wins[ 48:00 ] Side Effects Explained: What’s Actually Happening in Your Body[ 52:00 ] The “Flat Feeling”: Is GLP-1 Killing Joy?[ 56:00 ] The Future of GLP-1s: What’s Coming Next***🔥 Key TakeawayGLP-1s aren’t a shortcut—they’re a force multiplier.When combined with smart nutrition and resistance training, they unlock a level of transformation that most people never reach.***Get Connected with Elizabeth McGann:Coaching Website: http://www.ElizabethMcGann.comInstagram: http://www.instagram.com/elizabethmcgannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/elizabethmcgannX/Twitter: https://twitter.com/ElizabethMcGann***Learn more about Dr. Mike IsraetelNew Book The Aesthetic Revolution: https://www.amazon.com/Aesthetic-Revolution-Embracing-Fitness-Healthiest/dp/1538779846YouTube: https://www.youtube.com/channel/UCfQgsKhHjSyRLOp9mnffqVgInstagram: https://www.instagram.com/drmikeisraetel/Website for RP Strength/Renaissance Periodization: https://rpstrength.com/
- Apr 21, 202610 min
Why You Don’t Want to Lose Your Hunger on GLP-1
In this solo "mini-sode," Elizabeth McGann powerfully challenges one of the most common—and potentially harmful—misconceptions in the GLP-1 conversation: that hunger should disappear entirely. Drawing from her experience as a holistic nutritionist, Elizabeth reframes hunger not as the enemy, but as an essential signal the body needs to function, heal and thrive.She explores how over-reliance on GLP-1 medications can lead to disconnection from the body, loss of muscle, and long-term setbacks—and offers a more sustainable, empowering approach. By combining thoughtful medication use with foundational nutrition, metabolic support, and lifestyle strategies, listeners are invited to discover how to regulate hunger rather than suppress it.If you’re navigating GLP-1s—whether starting, adjusting, or considering a natural approach—this episode offers a mindset shift that could transform your results and your relationship with your body.***[ 0:00 ] Why We Need to Rethink Hunger on GLP-1 Medications[ 3:10 ] Why Chasing Zero Hunger on GLP-1 is Problematic[ 5:40 ] How to Find the Right GLP-1 Dose for Sustainable Weight Release[ 8:20 ] The Importance of Regulating Hunger Holistically for True FreedomGet Connected with Elizabeth McGannCheck out the new Youtube Channel! https://www.youtube.com/@ElizabethMcGannTubeInstagram: https://www.Instagram.com/ElizabethMcGannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/ElizabethMcGannX: https://twitter.com/ElizabethMcGann
- Apr 7, 20261h 15m
Before You Take GLP-1, Fix Your Gut (with Dr. Oscar Coetzee)
What if the real key to successful, sustainable weight loss isn’t starting a GLP-1—but fixing your gut first?In this eye-opening episode, I sit down with Dr. Oscar Coetzee, a leading expert in clinical nutrition and gut health, to unpack the critical (and often overlooked) role the microbiome plays in metabolism, cravings, and natural GLP-1 production.We explore why starting a GLP-1 with poor gut health can backfire, how specific bacteria influence hunger hormones and dopamine, and the emerging science behind “keystone” microbes that may control up to 85% of your metabolic function.If you’re considering a GLP-1, currently on one, or looking for a more natural, root-cause approach to weight loss—this conversation is essential.This episode will change how you think about your gut—and your path to lasting results.***SHOW NOTES[ 00:00 ] Introduction: A Critical Warning Before Starting GLP-1[ 04:00 ] Is the Gut Actually the First Brain?[ 08:00 ] From Psychology to Microbiome Medicine[ 12:00 ] The Microbes That Control Your Hunger Hormones[ 16:00 ] The Gut as an Ecosystem (The “Earthworm” Analogy)[ 20:00 ] Why Probiotics Alone Aren’t Enough[ 24:00 ] The Real Driver of Cravings and Overeating[ 28:00 ] The Fiber Crisis (and Why It Matters)[ 32:00 ] Signs Your Gut Is Holding You Back[ 36:00 ] Functional Testing: The Missing Diagnostic Tool[ 40:00 ] Why “Killing Bad Bacteria” Can Make Things Worse[ 44:00 ] The Breakthrough: Keystone (Anaerobic) Bacteria[ 48:00 ] Case Study: Reversing Food Sensitivities Naturally[ 52:00 ] How Gut Health Directly Drives GLP-1 Production[ 56:00 ] Why GLP-1 Results Plateau (and How to Fix It)[ 1:00:00 ] The 5 Bacteria That Control 85% of Your Metabolism[ 1:04:00 ] The Hidden Cost of GLP-1 Medications[ 1:08:00 ] Testing Your Metabolic Health Beyond the Scale[ 1:12:00 ] The Simplest (and Most Powerful) Gut-Healing Strategy[ 1:16:00 ] Final Takeaways: Build the Foundation First***Get Connected with Elizabeth McGann:Coaching Website: http://www.ElizabethMcGann.comInstagram: http://www.instagram.com/elizabethmcgannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/elizabethmcgannX/Twitter: https://twitter.com/ElizabethMcGann***Learn more about Dr. Oscar CoetzeeDr. Coetzee's Website: https://naturalhealthcarecenter.comInstagram: https://www.instagram.com/droscarcoetzee/
- Mar 24, 20261h 4m
How to Use GLP-1 Without Losing Muscle (with Dr. Zhenqi Liu)
What if the biggest mistake people are making on GLP-1 medications isn’t the drug—but how they’re using it?In this episode, Elizabeth sits down with leading endocrinologist and 20-year GLP-1 researcher Dr. Zhenqi Liu to unpack the hidden risks of rapid weight loss—including muscle loss, metabolic slowdown, and rebound fat gain—and how to avoid them.If you want to lose weight without sacrificing your metabolism, this conversation is essential.***SHOW NOTES[ 00:00 ] Introduction: The 7-Step GLP-1 Muscle Loss Cycle[ 03:30 ] Why Fast Weight Loss Backfires[ 07:00 ] Malnutrition: The Silent Risk[ 10:30 ] Why the Body Breaks Down Muscle First[ 14:00 ] Muscle Quality vs. Quantity in Obesity[ 17:30 ] Fat Inside Muscle & Metabolic Dysfunction[ 21:00 ] The Turning Point: Protecting Muscle During Weight Loss[ 24:30 ] Who Should Use GLP-1s (and Who Shouldn’t)[ 28:00 ] The Exercise Formula That Changes Everything[ 28:00 ] The Exercise Formula That Changes Everything[ 31:30 ] Cardiovascular Fitness & Longevity[ 35:00 ] Nutrition Mistakes That Undermine Results[ 38:30 ] “Eat Even If You’re Not Hungry”[ 42:00 ] Protein: The Non-Negotiable Nutrient[ 45:30 ] Protein + Strength Training: The Winning Combination[ 49:00 ] Protein Sources, Powders & Amino Acids[ 52:30 ] Are GLP-1s a Long-Term Solution?[ 56:00 ] Lower Doses & Smarter Use[ 59:30 ] The Rebound Effect Explained[ 1:03:00 ] The Most Common Mistakes People Make[ 1:06:30 ] Why Strength Matters More Than the Scale[ 1:10:00 ] Is Obesity a Disease?[ 1:13:30 ] Do You Need GLP-1s for Life?[ 1:17:00 ] The Real Secret to Sustainable Results**Get Connected with Elizabeth McGann:Coaching Website: http://www.ElizabethMcGann.comInstagram: http://www.instagram.com/elizabethmcgannFacebook: https://www.facebook.com/ElizabethMcGannWellnessLinkedIn: https://www.linkedin.com/in/elizabethmcgannX/Twitter: https://twitter.com/ElizabethMcGann***Learn more about Dr. Zhenqi LiuUniversity of Virginia Profile: https://med.virginia.edu/endocrinology-metabolism/research/endocrine-investigators/zhenqi-liu/X/Twitter: https://x.com/DrZhenqiLiu
- Mar 10, 202644 min
GLP-1 for Severe Obesity, PCOS and Binge Eating Disorder (with Rachael Gullette)
If you've been hearing about GLP-1 medications and wondering whether they might help you—but you feel nervous, skeptical, or unsure—this episode is a powerful place to begin. In this deeply personal conversation, Elizabeth sits down with GLP-1 advocate and content creator Rachael Gullette, who has lost more than 160 pounds on a GLP-1 medication. Rachael shares what life felt like before treatment, how food noise ruled her inner world, and how discovering that obesity is a disease—not a character flaw—changed everything. This is a raw, hopeful, eye-opening episode about food noise, binge eating, ADHD, shame, stigma, infertility, inflammation, and the kind of freedom that feels almost impossible until you experience it for yourself. *** SHOW NOTES [ 00:00 ] Introduction: A Different Kind of GLP-1 Story [ 03:00 ] "Everything Felt Heavy" [ 06:00 ] When Food Became Comfort, Dopamine, and Survival [ 09:00 ] Dieting Young, Without Understanding Why [ 12:00 ] The Discovery That Changed Everything: Obesity Is a Disease [ 15:00 ] Food Noise: What It Really Feels Like [ 15:00 ] "Someone Flipped a Switch" [ 21:00 ] ADHD, Binge Eating, and the Addiction Connection [ 24:00 ] The Early GLP-1 Community and the Stigma They Faced [ 27:00 ] TikTok Bans, Censorship, and Speaking Up Anyway [ 30:00 ] Obesity, Addiction, and Food Noise Exist on a Spectrum [ 33:00 ] A Hyper-Responder to GLP-1s [ 36:00 ] 160 Pounds Lost… and a Miracle Pregnancy [ 39:00 ] "It Is Not Your Fault" [ 42:00 ] Oprah, Public Stigma, and Why the Conversation Is Changing *** Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann *** Learn more about Rachael Gullette Instagram: https://www.instagram.com/lovenestconversation/?hl=en Linktree: https://linktr.ee/lovenestconversation
- Feb 24, 202652 min
How to Stop GLP-1's Without Gaining the Weight Back (with Dr. Holly Wyatt)
One of the biggest fears women have when starting GLP-1 medications isn't losing the weight —it's what happens after. Do I have to stay on this forever? Will I regain the weight if I stop? Is there a right way to transition into maintenance? In this powerful, science-grounded episode, Elizabeth sits down with Dr. Holly Wyatt—endocrinologist, obesity medicine physician, and author of Losing the Weight Loss Meds—to explore what actually helps people keep weight off long-term, with or without medication. This conversation bridges medical science with real-world behavior change, mindset, identity, and lifestyle—and fits seamlessly into the Holistic GLP-1 Method. If you're thinking about maintenance, transition, or long-term freedom from food struggle, this episode is essential listening. *** SHOW NOTES [ 00:00 ] Introduction [ 02:30 ] Why Dr. Wyatt wrote a book about getting OFF GLP-1s [ 03:55 ] Do you really have to stay on GLP-1s for life? [ 04:25 ] Why weight regain happens [ 05:20 ] What the data tells us (and what we're still learning) [ 07:45 ] GLP-1s as "training wheels" [ 08:30 ] Begin with the end in mind [ 09:05 ] The three pillars of successful maintenance [ 10:00 ] Why environment can make or break maintenance [ 11:20 ] Blood sugar, appetite & GLP-1 physiology (made simple) [ 13:25 ] Can lifestyle replace medication effects? [ 14:40 ] Quality vs. quantity of weight loss [ 15:20 ] The Appetite Reset Meal [ 17:40 ] Why breakfast matters more than you think [ 19:30 ] No dogma: one size never fits all [ 20:05 ] The Satiety Snack strategy [ 22:30 ] Physical activity is for maintenance, not weight loss [ 23:05 ] Metabolic flexibility explained [ 24:30 ] Why some people's weight never changes [ 26:10 ] The Supper Club strategy [ 27:55 ] The #1 mistake when stopping GLP-1s [ 29:40 ] Weight loss vs. weight maintenance are different phases [ 31:00 ] The 10-week transition plan overview [ 32:30 ] Microdosing: what we know and don't know yet [ 35:10 ] Side effects: what's normal and when to get help [ 37:35 ] Freedom as the real goal [ 42:15 ] Why weight loss alone doesn't create happiness [ 45:25 ] Food, addiction & filling life with more than food [ 46:15 ] Mind state vs. mindset [ 47:05 ] Identity shifts and long-term success [ 48:40 ] Menopause, midlife & possibility [ 52:00 ] Trusting your body without medication [ 54:00 ] Where to find Dr. Holly Wyatt [ 55:00 ] Final reflections *** 🔗 Mentioned in This Episode: Learn how to activate GLP-1 naturally and silence cravings! CLICK HERE TO GET ⇒ Free Masterclass: Freedom From Food Noise: https://go.elizabethmcgann.com/start *** Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann *** Learn more about Dr. Holly Wyatt Instagram: https://www.instagram.com/drhollywyatt/?hl=en Website and Book: https://www.weightwisdom.com/
About The Holistic GLP-1 Podcast with Elizabeth McGann
Stop doing GLP-1s wrong. Discover how to microdose, release weight and actually heal your body — on the world's #1-ranked podcast for holistic GLP-1 weight loss. Elizabeth McGann, holistic nutritionist, life coach, and microdosing GLP-1 user, shows women how to reach their happy weight, balance hormones and get their sexy back by activating their body's own GLP-1, often with less medication, or none at all. This isn't just weight loss. It's a full-life reboot! Through her signature program, Finally F*cking Free™, group and 1:1 coaching, she teaches The Holistic GLP-1 Method™ "where metabolic science meets intuition, and weight release becomes freedom in every dimension.
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