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This Week in Virology: Daily Summaries Delivered
by Vincent Racaniello
This Week in Virology is a netcast about viruses - the kind that make you sick.
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- Today1h 53m
TWiV 1363: A Cauldron of Bats
TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence are multi-causal, and that no one-size-fits-all strategy can prevent epidemics and pandemics, and an analysis of Myotis bats, which shows that their remarkable longevity and immunity are linked through pleiotropic adaptations to viruses and aging-related disease. Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Virus Appreciation Day (Day of the Year) Anthropogenic fingerprint on emerging infectious diseases (Nature) Longevity and virus-driven adaptations in Myotis bats (Nature) Letters read on TWiV 1363 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Angela – Birds. Alan – Halloween t-shirts from my local animal shelter. Vincent – A Thousand Brains by Jeff Hawkins Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- Yesterday53 min
TWiV 1362: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections, the absurdity of RFK Jr.’s statement that AI is better informed than physicians, the outbreak of cholera, more deaths by raw milk products, spread of dengue virus in Florida, Ebola in DRC, refusal to acknowledge the benefits of the HBV vaccine birth dose, how TORCH agent infections impact neurodevelopment and may lead to increase chances of autism diagnosis, Legionnaires disease and screw worm cases, before Dr. Griffin deep dives into recent statistics on RSV, influenza, SARS-CoV-2 infections, the continued measles outbreak in Pennsylvania, US, and Canada, modeling predictions of the outcome for repealing measles vaccination requirements to enter school in Florida, reactogenicity of different COVID vaccines and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode A.I. Is ‘Better Informed’ Than Doctors, Kennedy Tells Industry-Backed MAHA Summit (NY Times) WHO reports latest global trends in cholera, meningitis and plague (WHO) WHO: Global cholera deaths rose by 30% in2025 (CIDRAP) E. coli Outbreak Linked to Raw Milk Cheese (CDC: E. coli infection) CDC confirms multistate outbreak of E coli linked to raw milk cheese (CIDRAP) Dengue: Current Year Data (2026) (CDC: Dengue) Florida counties declare emergency over wildly unusual dengue outbreak (Washington Post) Critical role of hepatitis B birth dose vaccination in preventing mother-to-child transmission (CID) Effectiveness of timely hepatitis B birth dose vaccination to prevent mother-to-child transmission in Ethiopia (CID) Congenital TORCH Infections and Neurodevelopmental Outcomes (JAMA Pediatrics) Infections at birth substantially increase the risk of autism and intellectual disability, study finds (CIDRAP) UN Declaration on Pandemic Readiness May Head to General Assembly for Approval (Health Policy Watch) Legionnaires’ Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newro
- 1 weeks ago1h 46m
TWiV 1351: Ancient Viral Sword and Shield
TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Bob Tesh dies (Galv News) Comment on propsed changes to NIH peer review (NIH) NIH peer review proposed changes (Forbes) Ancient RNA guided DNA recognition (Science) Noncontiguous geometric triplex (Science) p-tau has anti-herpes virus activity (Nat Neurosci) Letters read on TWiV 1361 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – APoD September 14: Origins of Elements Alan – Redshirts, by John Scalzi Vincent – Prone to Bruise by David Molesky he’s at Spring/Break till 9/28 Listener Pick Anne – Nikon Small World in Motion Competition Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 1 weeks ago1h 0m
TWiV 1360: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy’s undermining of vaccines, perpetuation of autism- vaccine, autism-tylenol myths, an outbreak of hepatitis A virus in the US, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, Legionnaires disease and screw worm cases, and before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, economics of a measles outbreak in Chicago, what defines reactogenicity of the mRNA COVID vaccines, the on-going delay by HHS of COVID shots for children, neuropsychiatric symptoms of long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC adds 177 cases to US measles total but has yet to confirm deaths in Pennsylvania (CIDRAP) Kennedy questions vaccine safety at Children’s Health Defense event (CIDRAP) Trump says some routine immunizations will be split into five separate shots. Vaccine experts say it won’t work (CNN) Multistate Hepatitis A Outbreak Potentially Linked to Frozen Clams (CDC: Hepatitis A) Cumulative Incidence and Prevalence of Autism Spectrum Disorder (JAMA Pediatrics) Data and Statistics on Autism Spectrum Disorder (CDC: Autism Spectrum Disorder) Study uncovers no evidence of autism epidemic, despite claims (CIDRAP) Florida confirms a death from dengue as the state struggles with one of its worst recent outbreaks (AP News) Legionnaires’ Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Democratic Republic of Congo (AP News) Ebola virus (AP News) Congo begins Ebola vaccinations for health workers in the epicenter of the outbreak (AP News) Ebola dashboard (ebola.fyi) EBOLA: The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) <a href= "https://d
- 2 weeks ago1h 10m
TWiV 1359: SSPE, the Long Shadow of Measles
Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain selects for hyperfusogenic variants that spread neuron-to-neuron and cause subacute sclerosing panencephalitis, a rare but fatal long-term neurological sequela of measles infection. Host: Vincent Racaniello Guests: Roberto Cattaneo and Kalpana Yadav Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV How measles virus adapts to the brain (Ann Rev Virol) Measles virus F50S change in neuronal spread (J Virol) Measles virus collective infectious unit and SSPE (J Virol) Measles virus brain tropism acquisition (PLoS Path) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 2 weeks ago53 min
TWiV 1358: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, establishing an NIH research center on vaccine harms, Legionnaires at Yankee stadium and the first time in more than half a century reporting of an equine screwworm case, and how HHS may prevent more than half of US children from getting the COVID-19 vaccine this season before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, efficacy and safety of the 2026-2027 COVID-19 vaccine, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Unvaccinated Woman Likely Died of Measles Complications, Pa. County Coroner Says NY Times) Confirmed death of an 18-year old due to complications of measles (Facebook: Mifflin County Coroner’s Office) CDC’s new tracking method for measles deaths puzzles experts (CIDRAP) Kennedy to deliver keynote for anti-vaccine group he once led (STATNews) Exclusive: New NIH research center on vaccine harms takes shape (Science) US pediatricians report seeing fewer patients because of immigration enforcement worries (CIDRAP) Surgeon General Nominee Pledges Support for Vaccines in Senate Hearing (NY Times) CIDRAP Op-Ed: HHS is asking what to call vaccine recommendations. You have 4 days to weigh in. (CIDRAP) 21,000 Unvaccinated Children Are Not a Minor Problem, But a Warning Sign (GPEI) Researchers file First Amendment challenge to NIH grant screening (Science) Cooling towers at Yankee Stadium test positive for Legionnaires’ in new cluster (NBC News) Legionnaires’ Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Texas ranch horse becomes nation’s <a hr
- 3 weeks ago1h 44m
TWiV 1357: Furin, Naturally with Paul Bieinasz
Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per genome, including new furin cleavage sites at the spike S1/S2 junction. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Genetic innovation in coronaviruses driven by a viral nuclease (bioRxiv) Letters read on TWiV 1357 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Kathy – Jurassic Museum of Asturias Alan – Grand Central Winter, by Lee Stringer Vincent – How to Choose REAL Extra Virgin Olive Oil: A Practical Guide and How to Tell if Your Olive Oil is Fake! Quick Kitchen Tip! Listener Pick Shirley – I Told You So! by Matt Kaplan Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 3 weeks ago47 min
TWiV 1356: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed changes in biomedical funding including “converting” the Department of War into NIAID, the continuing controversy over the deaths of 2 children in Pennsylvania from measles, before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, approval of new mRNA COVID-19 vaccines by the FDA, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Dengue in Florida: Florida Arbovirus Surveillance (Florida Health) Nationwide Increase in Reported Human Rabies Exposures: Rabies Post-exposure Prophylaxis Administration (CDC: Health Alert Network) NIH proposes major revamp of how it scores research grant proposals (Nature) Revealed: inside the US military’s plan to tap huge sums from the NIH (Nature) Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey-Teen, United States, 2025 (CDC:MMWR) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola dashboard (ebola.fyi) EBOLA: The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Notes from the Field: Clinical Characteristics of Patients with Ebola Disease Caused by Bundibugyo Virus — Uganda, 2026 (CDC: MMWR) Notes from the Field: Characteristics and Monitoring of the 2026 Outbreak of Ebola Disease Caused by Bundibugyo Virus — Democratic Republic of the Congo, August 2026 (CDC:MMWR) <a href= "https://data.wastewaterscan.org/tracker/?charts=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