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Immune: Daily Summaries Delivered
by Vincent Racaniello
A podcast about the body's defenders against disease.
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The most recent episodes — sign up to get AI-powered summaries of each one.
- Yesterday1h 3m
Immune 106: Science and podcasting with Kathryn Knoop and Marion Brunck
Kathryn Knoop and Marion Brunck join the Immune team to talk about their research and their podcast "Mucosal Immunology". Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker Guests: Kathryn Knoop and Marion Brunck Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Knoop: Oral tolerance in early life review Knoop: Gamma delta T cells in neonatal sepsis Knoop: EGF and IgA in breastmilk Brunck: FcGR's in PMNS Brunck: CRISPR KO to study FcGR's in human PMN Brunck: Leukocytes in breastmilk review Mucosal Immunology podcast Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- 1 weeks ago42 min
Immune Booster 32: Natural infection versus vaccine protection with Jenna Guthmiller
Jenna Guthmiller talks about how she became interested in immunology and her exciting research on how different responses to vaccines and infection shape future responses to infection. Host: Cindy Leifer Guest: Jenna Guthmiller Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Broadly neutralizing flu antibodies (Nature, 2022) First exposure antibodies to H1N1 flu (Sci Transl Med, 2021) Long lasting B cells to chimeric flu vaccine (Immunity, 2025) Vaccine strategies to target HA anchor epitope (Nat Comm, 2025) Pre-existing immunity shapes flu response (Sci Trans Med, 2020) From Immune 35: SARS-CoV-2 infection severity linked to anti-spike (mBio, 2021) Guthmiller lab Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- 4 weeks ago1h 1m
Immune 105: Tumor bacteria undermine immunotherapy
Immune discusses a snippet on how EBV infection alters the immunopeptidome and promotes multiple sclerosis, and a paper on head and neck cancers harboring bacteria that create an immunosuppressive environment and promote immunotherapy resistance. Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server EBV, Golli-MBP presentation and multiple sclerosis (Cell, 2026) Intratumoral bacteria promote resistance to cancer immunotherapy (Nat Cancer, 2026) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- Jun 23, 202640 min
Immune Booster 31: NOD-like receptor discovery with Gabriel Nunez
Gabriel Nunez discusses the discovery of NOD-like receptors, NOD1 and NOD2, in inflammatory bowel disease and how travel and taking a moment to enjoy local culture and art influences his creativity. Host: Cindy Leifer Guest: Gabriel Nuñez Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server HLA and antigen presentation (Hum Immunol, 1987) Bcl2, cell death, and B cells (Nature, 1991) Discovery of NOD1 (J Biol Chem, 1999) Discovery of NOD2 (J Biol Chem, 2001) Mutation in NOD2 and connection to Crohn's disease (Nature, 2001) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- Jun 9, 202649 min
Immune Booster 30: Infant Immunology with Martha Alexander-Miller
Martha Alexander-Miller discusses why newborn and infant immune responses to vaccines are generally less effective and how we can make vaccines safer and more effective. Host: Cindy Leifer Guest: Martha Alexander-Miller Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Flu HA nanoparticle vaccine (Nat Comm, 2025) Sex-dependent adjuvant activity in newborns (Vaccines, 2024) Flu vaccine with R848 adjuvant (Vaccines, 2023) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- May 26, 20261h 20m
Immune 104: All about allergies
The Immune team talks about two papers on the effect of sleep and environment on seasonal allergies. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Sleep is needed for condition dependent allergic responses (PNAS, 2020) Original paper on allergy to artificial rose (Am. J. Med. Sci. 181, 45–56 (1886)) One of multiple personalities allergic (Am J Clin Hypn, 1983) Environmentally driven immune imprinting protects against allergy (Nature, 2026) News and Views on immune imprinting paper (Nature, 2026) Immune 90 discussion of "dirty mice" Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
- May 20, 20261h 3m
Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology
Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology May 19, 2026 Today Dr. Kevin Kohl, Associate Professor of Biological Sciences at the University of Pittsburgh, joins the #QualityQuorum to discuss how he and his colleagues study the interplay between animals, their resident gut microbes, and the overarching concept of the holobiont. Host: Mark O. Martin Guest: Kevin Kohl Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The One Health Microbiome Center at Pennsylvania State University. A very fine essay on the holobiont concept for non-microbiologists. A general introductory overview of the holobiont concept. The holobiont concept and the coral symbiosis. A partial history of the development of the holobiont concept. Dr. Casadevall suggests that context and thus outcomes describes the term "pathogen," and a similar analysis applies to the holobiont. A very short description of the holobiont concept. Another overview of the holobiont concept in general, coauthored by Dr. Kohl. Some basic rules for thinking about the holobiont concept. A video introduction to the holobiont concept, by Dr. Seth Bordenstein. I highly recommend this essay by the science writer Carl Zimmer, "The Human Lake," to think of the connections between lake ecology and microbial interactions with humans. Another wonderful article recommended by Dr. Kohl, by Dr. Margaret McFall-Ngai and coauthors, detailing the impact microbes have on animals over evolution and development. The wood rat – creosote – microbiome connection to the holobiont concept, discussed on this podcast (coauthored by Dr. Kohl). The fascinating work by Dr. Kohl and colleagues showing the relationship between tadpole development and pond microbes discussed in this podcast. A must read article by Dr. Kohl and colleagues, "Through the microbial looking glass: our shifting understanding of the holobiont and microbes as mediators of organismal biology," illustrates the development and influence of the holobiont concept. Dr. Richard Prum's book, "Performance All the Way Down," was discussed during this podcast. There is also a video where Dr. Prum discusses the ideas in this book, describing gene regulation as a performance. Dr. Kohl's faculty website. Dr. Kohl's (very interesting) research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
- May 19, 202631 min
Immune Booster 29: Immune regulation and science communication with Nicholas Jackson
Nicholas Jackson, AKA Nick the Immunologist, talks about being a graduate student, social media creator, and his research on cytokine tools to investigate regulatory T cells. Host: Cindy Leifer Guest: Nicholas Jackson (Nick the Immunologist) Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Richard DiPaolo lab IL-2, TGFb and Tregs preprint Nick the Immunologist on TikTok Nick the Immunologist on Instagram Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
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A podcast about the body's defenders against disease.
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It's a free AI-powered email that summarizes new episodes of Immune as soon as they're published. You get the key takeaways, notable quotes, and links & mentions — all in a quick read.
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Immune publishes weekly. Our AI generates a summary within hours of each new episode.
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