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Extend Podcast with Darshan Shah, MD: Daily Summaries Delivered
by Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Latest Episodes
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- Yesterday52 min
185. Dr. Neha Sangwan: The 5 Questions That Predict a Health Crisis Before It Happens
I have operated on patients whose bodies had been sending them warning signals for years before a crisis ever put them in front of me. Stress alone causes or worsens more than 80 percent of the illness I see, and most of it traces back to one skill almost nobody was ever taught: how to actually listen to their own body. We dive deeper into this in the Extend Podcast with Dr. Neha Sangwan. We also chat about the five questions she asks every patient before sending them home, why your boss has more influence on your health than your doctor does, and the five levels of connection that determine whether a relationship heals you or drains you. Dr. Neha Sangwan is an internal medicine physician and former hospitalist who also trained as a mechanical and biomedical engineer. She is the founder and CEO of Intuitive Intelligence, where she works as an executive health and performance coach for corporate leaders and their teams. She is the author of TalkRx: Five Steps to Honest Conversations that Create Connection, Health, and Happiness, and Powered by Me: From Burned Out to Fully Charged at Work and in Life. What We Discuss: Why training as both a mechanical engineer and a physician led straight to burnout at 34. The Awareness Prescription: the five questions she asks every patient the night before discharge. The Body Map: how physical signals are data your doctor never sees. Why your leader has more influence on your health than your doctor does. The five-step framework for walking into any hard conversation clearly and calmly. The five-hour shift and the question from a nurse that first told her she was burning out. Net gain versus net drain: mapping where your energy leaks and where it grows. The five levels of exchange, from broken to sacred. Thank You to Our Sponsors: Next Health Longevity Summit: Head to next-health.com/summit to secure your spot at the first ever Next Health Longevity Summit in Nashville on 9/12. Function Health: Learn more and join using my link. Visit www.functionhealth.com/drshah and use gift code DRSHAH25 for a $25 credit toward your membership. Learn more about Dr. Shah: Website: drshah.com Clinic: next-health.com Instagram: @darshanshahmd Learn more about Dr. Neha Sangwan: Website: intuitiveintelligenceinc.com/ Instagram: @doctorneha LinkedIn: drnehasangwan Book: intuitiveintelligenceinc.com/powered-by-me/
- 6 days ago1h 6m
184. Dr. Sahil Chopra & Sagar Chopra: Why Your Sleep Apnea Machine Might Be Lying to You
Millions of people wear a CPAP machine every night, the standard breathing device prescribed for sleep apnea. They trust the number on the screen to tell them their sleep apnea is under control. I've had patients tell me they stopped using theirs because it felt pointless, and it turns out that feeling was often correct. We dive deeper into this in this episode of Extend with Dr. Sahil Chopra and Sagar Chopra, co-founders of Empower Sleep. We also chat about why palate shape and mouth breathing are driving more sleep apnea in kids, how GLP-1 medications are changing the CPAP conversation, and the truth about lip taping. Dr. Sahil Chopra is a pulmonary, critical care, and sleep medicine physician trained at UCLA and Loma Linda, with fellowship training in sleep medicine at Harvard. He is co-founder of Empower Sleep, a longitudinal home sleep testing platform used by physicians and patients nationwide. Sagar Chopra holds an MBA from the Wharton School, previously worked on product growth at Uber, and co-founded Empower Sleep alongside his brother, Dr. Sahil Chopra. What We Discuss: The Landmark Study: 25,000 Nights of Data and the CPAP Discordance Problem Inside the Empower Sleep Device and How It Differs From Wearables Palate Shape, Mouth Breathing, and the Rise of Pediatric Sleep Apnea Menopause, Andropause, and Why Sleep Apnea Shows Up Later in Life Hypoglossal Nerve Stimulators and Central Sleep Apnea How GLP-1 Medications Are Changing Sleep Apnea Treatment The Truth About Lip Taping and Nasal Breathing Thank You to Our Sponsors: Next Health Longevity Summit: Head to next-health.com/summit to secure your spot at the first ever Next Health Longevity Summit in Nashville on 9/12. Momentous: Head to livemomentous.com/fiber and use code DRSHAH for up to 35% off your first order. Learn more about Dr. Shah: Website: drshah.com/ Clinic: next-health.com/ Instagram: @darshanshahmd Learn more about Dr. Sahil Chopra and Sagar Chopra: Empower Sleep: empowersleep.com/ Sagar Chopra on LinkedIn: choprasagar/ Sagar Chopra on X: schopsss More Resources: Quality sleep is the most underestimated longevity accelerator. Download this sleep optimization workbook to transform sleep into a powerful longevity practice: drshah.com/sleep
- 1 weeks ago53 min
183. Rachel Lambert & Angie Noack: Why 70% Of ADHD Diagnoses Are Wrong
For most people, an ADHD diagnosis, an anxiety diagnosis, or a depression diagnosis is made entirely from a symptom checklist. No one looks at the brain producing those symptoms. In this episode, I sit down with Rachel and Angie, co-founders of BrainCode Centers, to talk about quantitative EEG brain mapping and neurofeedback, and why measuring the brain's actual electrical activity changes the picture so often. We look at why the majority of people carrying an ADHD diagnosis do not show the neurological pattern for it, what depression and anxiety actually look like on a brain scan, and how reward-based neurofeedback training retrains those patterns without medication. Rachel and Angie are licensed professional counselors and board certified in neurofeedback. Over seventeen years, they have mapped and trained roughly 25,000 brains, built in-person clinics across Denver, Boulder, Tulsa, and Dallas, and developed a remote kit that lets anyone get a brain map and begin neurofeedback training from home. What's Discussed: What a brain map actually measures, and why it is not a CT scan or a blood flow test. The five brain waves everyone produces, and what happens when the brain gets stuck in one of them. How a remote EEG kit lets someone map their own brain from a swim cap at home. How neurofeedback works as reward-based training instead of willpower or medication. What depression actually looks like on a brain scan, and why the DSM diagnosis often misses the real driver. Why the majority of people carrying an ADHD diagnosis do not show the neurological pattern for it. What anxiety looks like across ten completely different brain patterns. Angie's own bipolar diagnosis as a teenager, and how forty sessions of training changed the scan. Listen to this episode to learn why a diagnosis deserves an actual look at the brain behind it, before medication becomes the only conversation. Thank You to Our Sponsors: Next Health Longevity Summit: Head to next-health.com/summit to secure your spot at the first ever Next Health Longevity Summit in Nashville on 9/12. IM8: Try IM8 today with a 30-day money back guarantee. Get 10% off your first order with code DRSHAH at im8health.com/discount/DRSHAH . Momentous: Head to livemomentous.com/fiber and use code DRSHAH for up to 35% off your first order. Timeline: Timeline powered by Mitopure just dropped the price. Check it out at timeline.com/drshah and get an additional 20% off your first month with code DRSHAH. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About BrainCode Centers: Website: braincodecenters.com Instagram: @braincodecenters
- 1 weeks ago57 min
182. Michael Easter: The Hidden Health Cost of Modern Comfort
A lot of people do not need to be convinced that the stairs are better than the escalator, walking is better than sitting all day, and reaching for the phone every quiet second is probably not helping their focus. The harder question is why the easier option still wins so often, even when someone cares about their health. This episode starts there, with the strange gap between what we know is good for us and what modern life quietly trains us to choose. In this episode of Extend, I sat down with Michael Easter to look at the hidden cost of a life designed around ease. The conversation asks what happens when discomfort, movement, boredom, load, scarcity, and friction are removed from daily life, and why putting some of those inputs back may change the way we think about resilience, behavior, and long-term health. Michael Easter is the author of The Comfort Crisis and Scarcity Brain, and the creator of the Two Percent newsletter and podcast. His work sits at the intersection of science, human behavior, fitness, and real-world experience, making him the right person to explain why the modern world can pull us away from the very things that help the body and brain stay adaptable. What's Discussed: The striking gap between how much humans move today versus how much we evolved to move and what that gap is quietly doing to our health. The one statistic that explains why most people consistently choose the thing they know is worse for them even when the better option is right in front of them. The exercise that humans are uniquely built to do, that has almost completely disappeared from modern life and why bringing it back changes everything. The specific treadmill protocol Michael uses that builds endurance and strength simultaneously without the injury risk most people associate with cardio. Why solitude and loneliness are not the same thing and what the research actually shows about what happens when you learn to be alone with yourself. The three-part psychological loop behind slot machines that was deliberately engineered into the technology most people use every single day. What a study on one of the most unlikely populations in America revealed about why movement and community can offset almost everything else we get wrong about health. Listen to this episode of Extend to understand why the healthier choice is not always a knowledge problem, why comfort can quietly shape behavior, and how the right kind of friction may help your body and mind become more resilient over time. Thank You to Our Sponsors: Momentous: Head to livemomentous.com/fiber and use code DRSHAH for up to 35% off your first order. Next Health Summit: Head to next-health.com/summit to secure your spot at the first ever Next Health Longevity Summit in Nashville on 9/12. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About Michael Easter: Website: TWOPCT.com Substack: Two Percent with Michael Easter Book: The Comfort Crisis Book: Scarcity Brain
- 2 weeks ago49 min
181. Dr. Taz: The Hormone Conversation Women Should Have Before Birth Control, IVF, or HRT
For many women, the hormone conversation starts only when something becomes hard to ignore. Painful periods. Irregular cycles. Acne. Hair loss. Fertility struggles. Perimenopause symptoms. Too often, the answer is a quick fix for the symptom in front of them, without anyone asking what the body was trying to signal years earlier. In this episode, I sit down with Dr. Taz Bhatia MD to talk about why women's hormone health needs to be understood across the entire lifespan, not as separate problems that show up during adolescence, fertility, perimenopause, or menopause. We look at why symptoms like bad periods, PMOS, fatigue, mood changes, inflammation, weight gain, and hormone shifts should be connected back to the gut, metabolism, stress, nutrient status, inflammation, and emotional health. Dr. Taz Bhatia MD, brings a rare mix of conventional medical training and integrative medicine experience to this conversation. She began her career in emergency medicine, then expanded her work through holistic medicine, Chinese medicine, acupuncture, nutrition, and integrative medicine training through Dr. Andrew Weil's fellowship. Her own experience with fatigue, hair loss, joint pain, weight changes, and PMOS also shaped the way she helps patients look beyond symptom management and understand the full body story behind their health. Important note: This episode was recorded before PCOS was formally renamed PMOS (Polyendocrine Metabolic Ovarian Syndrome). Throughout this conversation, you'll hear the term PCOS, as it was the standard name at the time of recording. The new name was adopted to better reflect that the condition is a complex hormonal and metabolic disorder affecting multiple body systems—not just the ovaries—and because many people with the condition do not actually have ovarian cysts. What's Discussed: Dr. Taz Bhatia's own health struggles and why conventional medicine did not give her the answers she needed. Why people need a medical home that helps them stay well, not just emergency care when something goes wrong. How symptoms act as early signals from the body, and why health needs to be looked at across physical, emotional, cognitive, spiritual, and community layers. Why women's hormone health should start in adolescence, not when perimenopause or infertility begins. Why PMOS is not just about ovarian cysts and how blood sugar, insulin resistance, gut health, stress, and inflammation can drive symptoms. What women need to understand about long-term birth control use, nutrient depletion, inflammation, and hormone suppression. Why birth control options should be part of a deeper conversation about the individual, not an automatic prescription. Listen to this episode to learn why women deserve a better hormone conversation before they reach the crisis points of birth control, IVF, or HRT. Thank You to Our Sponsors: Next Health: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at next-health.com/ IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at im8health.com/discount/DRSHAH. Momentous: Head to livemomentous.com/fiber and use code DRSHAH for up to 35% off your first order. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About Dr. Taz Bhatia MD Website: doctortaz.com Instagram: @drtazmd
- 2 weeks ago57 min
180. Dr. John Kim: The Hidden Stressors Keeping Your Body in Defense Mode
When labs look normal, it is easy to assume the body is fine or that the biggest risks have been ruled out. Dr. John Kim's story challenges that belief. At 33, after a normal lipid panel and without the classic heart attack picture, he ended up with an 85% blockage in his LAD. That experience forced him to ask what standard markers were missing. The answer led him into the deeper cellular stressors that can keep the body in defense mode: mold, mycotoxins, chronic infections, biofilms, heavy metals, emotional trauma, gut dysfunction, damaged cell membranes, and mitochondrial stress. In this episode of Extend, I sit down with Dr. Kim to talk about how these stressors can push the mitochondria away from energy production and into the cell danger response, where the body is still trying to protect itself but starts paying the price through brain fog, fatigue, inflammation, hormone disruption, gut issues, and hypersensitivity. Dr. John Kim is a functional pharmacist whose work focuses on mold toxicity, mitochondrial health, lipid membrane medicine, chronic infections, gut health, and structured detox support. This episode gives listeners a new framework for symptoms that do not make sense on standard labs, from brain fog and fatigue to chronic inflammation, hormone disruption, gut issues, and hypersensitivity, while showing why recovery has to happen in the right sequence before the body can fully rebuild. What's Discussed: The heart attack at 33 that doctors almost missed. Why a normal lipid panel did not explain what was happening underneath. Why heart disease goes beyond cholesterol. How biofilms can hide chronic infections from the immune system. What the cell danger response does to mitochondria and energy production. Why mold and mycotoxins can affect the brain, gut, immune system, and hormones. How the ENCORE method helps sequence recovery from mold and cellular stress. Listen to this episode of Extend to understand why "normal" does not always mean resolved, how hidden stressors can keep your cells on defense, and why recovery may need to start with the environment, nervous system, gut, detox pathways, and cell membrane before deeper healing can happen. Thank You to Our Sponsors: Next Health Longevity Summit: Head to next-health.com/summit to secure your spot at the first ever Next Health Logevity Summit in Nashville on 9/12. IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at im8health.com/discount/DRSHAH. Momentous: Head to livemomentous.com/fiber and use code DRSHAH for up to 35% off your first order. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About Dr. John Kim, Pharm.D. Website: drjohnkim.com/ Instagram: @john.pharmd
- 3 weeks ago46 min
179. Dr. Scott McMahon: The Hidden Trigger Behind Your Unexplained Symptoms
Most people assume that once they leave a mold-exposed building, their body should recover. But I see this all the time in my clinic, the mold exposure ends, and the symptoms don't. In this episode of Extend, I sit down with Dr. Scott McMahon, medical director at MoldCo, to ask why removing the source doesn't always mean removing the illness. We get into a switch inside the immune system, one that determines whether the body can actually call off an inflammatory response once a threat is gone, and what happens when that switch stops working. Understanding it changes how a long list of unexplained, lingering symptoms starts to make sense. Dr. Scott McMahon spent eighteen years as a pediatrician before a case involving a group of sick high school students redirected the entire focus of his career. He went on to study under Dr. Richie Shoemaker, the physician who first identified Chronic Inflammatory Response Syndrome (CIRS), and has spent years treating patients, publishing research on the condition's diagnostic criteria, and co-authoring a book on CIRS medicine. As medical director of MoldCo, he now works at the intersection of testing, treatment, and education for a condition that affects an estimated one in four people genetically, making him one of the most credible voices in the country on this topic. What's Discussed: The high school case that revealed how multi-system illness can hide behind symptoms doctors are trained to treat separately. The difference between a mold allergy and a full immune system malfunction, and why they are not the same thing. What determines whether one person's body can shut off inflammation and another person can't. The ten lab markers that can actually confirm what's happening, and why most physicians have never ordered them. Why a popular at-home mold test might be telling you less than you think. How to check your own home for the signs most people walk right past. The real number of people walking around with this genetic predisposition, and why it's higher than almost anyone expects. If symptoms have stuck around well after leaving a mold-exposed space, this conversation breaks down why, and what's actually keeping the body in that state long after the exposure ended. Thank You to Our Sponsors: Next Health: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at next-health.com/ Function Health: Learn more and join using my link. Visit functionhealth.com/drshah and use gift code DRSHAH25 for a $25 credit toward your membership. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About Dr. Scott McMahon: Website: scottmcmahon.doctor Instagram: @drscottmcmahon LinkedIn: dr-scott-mcmahon Latest book: The Art and Science of CIRS Medicine
- 3 weeks ago1h 14m
178. Dr. Matt Kaeberlein: The Science, Risk, and Hype Behind Today's Longevity Trends
If you care about longevity, you have probably seen the same pattern over and over again. A new peptide, supplement, biological age test, off-label drug, or protocol starts gaining attention, and suddenly it sounds like the missing piece everyone should be using. The hard part is not wanting to be proactive. The hard part is knowing which claims have real evidence behind them, which ones are still early signals, and which ones may carry risks no one is measuring carefully enough. In this episode, I sit down with Dr. Matt Kaeberlein to talk about how to think about longevity when the answer is rarely a simple yes or no. This conversation helps separate excitement from certainty, and shows why the real question is not only whether something might work, but whether the evidence, safety data, product quality, and risk-reward equation are strong enough to act on. Dr. Matt Kaeberlein is a scientist in the biology of aging and one of the most respected voices bringing scientific discipline to the longevity conversation. He has been involved with the Interventions Testing Program, which rigorously tests aging interventions in mice, and is one of the leaders behind the Dog Aging Project, a large-scale study looking at aging, health, and longevity in companion dogs. His work sits at the intersection of curiosity and caution, which makes him the right person to talk about what is promising, what is overhyped, and what still needs better evidence. What's Discussed: Why longevity marketing can move faster than the science. The risk-reward question most people skip before trying a new therapy. Why years of peptide use does not automatically mean safety is proven. The "research use only" peptide problem and why product quality matters. How the Interventions Testing Program separates stronger longevity signals from noise. Why rapamycin changed the field, and why some popular interventions failed to replicate. What the Dog Aging Project may teach us about rapamycin, healthspan, and human aging. Listen to this episode of Extend to understand how to evaluate longevity claims with more clarity. You will hear what deserves excitement, what deserves caution, and what to ask before turning the next promising intervention into your personal health protocol. Thank You to Our Sponsors: Timeline: Timeline powered by Mitopure just dropped the price. Check it out at timeline.com/drshah and get an additional 20% off your first month with code DRSHAH. IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at im8health.com/discount/DRSHAH. Learn More About Dr. Darshan Shah: Website: drshah.com Clinic: next-health.com Instagram: darshanshahmd Learn More About Dr. Matt Kaeberlein & the Dog Aging Project: Website: dogagingproject.org/ Instagram: @mkaeberlein
About Extend Podcast with Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
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