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Menopause Mastery: Daily Summaries Delivered
by Dr. Betty Murray
Welcome to Menopause Mastery with Dr. Betty Murray. This show is for women in the second season of life, the season of menopause, who are ready for more: health - vitality - passion - and purpose! Join host, Dr. Betty Murray (part geek, part magician, and your new medical bestie with a dash of sass), as she takes complex science and makes it easier to integrate into daily life. Nutrition, hormones, functional medicine, and a wellness lifestyle are only the tip of the conversation. Join the journey to uncover your deepest desires, harness your physical and mental health, and peel back the layers to know exactly what you want out of life.
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- 4 days ago54 min
Glutathione, Menopause, & Aging: The Missing Piece in Oxidative Stress and Why It Matters
Menopause Mastery | Glutathione, Menopause, & Aging: The Missing Piece in Oxidative Stress and Why It Matters | Ep. 298 with Dr. Gina Nick 🌿Welcome to The Menopause Mastery Show! What if some of the changes women experience during perimenopause and menopause are connected to more than changing hormone levels? In this episode, Dr. Betty Murray dives into oxidative stress, inflammation, detoxification, and the role glutathione may play in supporting the body's natural processes. Dr. Gina Nick, a naturopathic physician, researcher, and expert in detoxification, joins the conversation to explain how she became focused on glutathione and why she believes supporting the body's detoxification and antioxidant systems deserves more attention during midlife. We discuss the relationship between estrogen changes, oxidative stress, inflammation, mitochondrial health, and the symptoms women commonly experience during menopause. In this episode, we discuss: * Dr. Gina Nick's journey into naturopathic medicine and detoxification and what research went into creating Vitamin G™ * What oxidative stress means in the context of women's health * Glutathione and its role inside the cells * The relationship between estrogen changes, inflammation, and menopause * Neuroinflammation, brain fog, anxiety, and mood changes * Oxidative stress and cardiovascular health * What the body's natural detoxification system actually does * Why daily detox-supporting habits can matter * The potential drawbacks of extreme fasting and detox protocols * Why "more" glutathione isn't necessarily better * The importance of zinc, magnesium, B vitamins, and other cofactors * Genetics and individual differences in glutathione pathways * Supplement marketing and navigating health information online * Glutathione, the liver, and hormone metabolism * Dr. Gina's association with Menrva * The future of personalized menopause care and women's health research Menopause is a complex transition involving far more than a single hormone. This conversation explores how hormones, inflammation, oxidative stress, detoxification, lifestyle, genetics, and individualized care can intersect—and why looking at the whole picture may be important when supporting women through midlife. ✨🌿 👉 For more evidence-based conversations about perimenopause, menopause, hormones, brain health, sexual health, and the research shaping women's health, don't forget to subscribe! @drbettymurray To connect with Dr. Gina: https://drgina.com/ https://www.instagram.com/drginanick Find Vitamin G™ here: https://vitaming.com/ 00:00 – Intro: Dr. Gina Nick & Glutathione 01:09 – Dr. Gina's Journey Into Detoxification 03:12 – How Glutathione Became Her Focus 04:36 – Creating Vitamin G™ 07:45 – What Glutathione Does in the Body 09:14 – Oxidative Stress & Menopause 12:25 – Glutathione, Inflammation & Menopause Symptoms 14:20 – Neuroinflammation, Brain Fog & Mood 16:42 – Glutathione & Cardiovascular Health 20:20 – Supporting the Immune System 22:33 – What Detoxification Really Means 24:12 – Everyday Ways to Support Detoxification 27:00 – Detoxes, Fasting & Menopause 31:18 – Are Glutathione IVs Really Better? 32:26 – How Glutathione Gets Recycled 33:25 – Why More Glutathione Isn't Always Better 36:31 – Genetics & Glutathione 38:12 – Why a Whole-Body Approach Matters 40:20 – Glutathione, Travel & Radiation Exposure 42:11 – How Vitamin G Was Formulated 44:12 – Glutathione & Liver Detoxification 45:34 – Introducing Minerva 47:10 – Personalized Menopause Care 49:19 – The Future of Women's Health Research 50:30 – Building Better Women's Healthcare 52:16 – Why Women Deserve Better Healthcare 53:29 – Where to Find Dr. Gina Nick 54:36 – Closing 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts→ https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time. 🌱 #menopausemastery #menopausepodca
- 1 weeks ago38 min
Why Stress Makes Menopause Symptoms Worse (and What to Do About It)
Menopause Mastery | Why Stress Makes Menopause Symptoms Worse (and What to Do About It) | Episode 297 🌿Welcome to The Menopause Mastery Show! 🤔 What if your menopause symptoms aren't just about declining sex hormones? In this episode, Dr. Betty Murray takes a deeper look at the relationship between chronic stress, the HPA axis, thyroid function, blood sugar regulation, and ovarian hormone production. When the body's stress-response system stays activated, it can affect multiple interconnected systems—and that may help explain why some women continue to struggle even when they're using hormone replacement therapy. ✅ You'll learn: * How the hypothalamus, pituitary, and adrenals communicate * Why chronic stress can disrupt hormone signaling * The connection between stress, thyroid function, and sex hormones * Why blood sugar swings can reinforce the stress response * What 3 a.m. waking may tell you * Morning light and circadian rhythm * Protein-forward meals and blood sugar stability * Why more intense exercise isn't always better * The importance of recovery and sleep * Nervous-system regulation and somatic practices * Where magnesium, phosphatidylserine, and adaptogens may fit * Why a broader systems approach may be important when HRT isn't producing the expected results The episode also covers practical strategies for supporting nervous-system regulation, circadian rhythm, blood sugar stability, exercise recovery, and sleep. We also discuss where supplements may fit—and why they shouldn't be expected to compensate for chronic stress, poor sleep, inconsistent eating, or excessive exercise. 🌿✨ 00:00 — Why stress may be the missing piece in menopause 01:22 — Why your adrenals can't replace the ovaries 02:40 — The HPA axis: the system above the other systems 03:32 — How the stress-response system actually works 05:00 — What chronic stress does to cortisol signaling 05:52 — Acute stress vs. chronic stress 06:47 — How chronic stress can suppress ovarian function 08:02 — Allostatic load vs. "adrenal fatigue" 09:08 — Stress, inflammation, the nervous system and sleep 10:02 — Why you may be waking up at 3 a.m. 10:49 — The stress–blood sugar–cortisol connection 11:15 — Perimenopause, weight gain and the metabolic stress cycle 12:34 — Why declining estrogen can compound the problem 13:09 — The truth behind the "pregnenolone steal" concept 14:09 — Why progesterone is especially vulnerable in early perimenopause 15:12 — Stress and the thyroid connection 16:11 — T3, reverse T3 and thyroid conversion 17:27 — The stress–thyroid–sex hormone triangle 18:08 — How to start regulating the nervous system 18:55 — Physiological sighs and extended-exhale breathing 19:46 — Cold exposure and nervous-system regulation 20:33 — Humming, chanting and parasympathetic activation 21:03 — Morning light and circadian anchoring 22:19 — Why your "second wind" may not mean you're a night owl 23:38 — Light exposure and metabolic regulation 24:05 — Blood sugar stabilization 24:42 — Why a protein-forward breakfast matters 25:04 — Carbohydrates, blood sugar and menopause 25:31 — Exercise, recovery and the HPA axis 26:35 — Why training splits can support recovery 27:44 — Zone 2 cardio and exercise intensity 28:44 — Why sleep is non-negotiable 29:26 — Somatic practices for nervous-system regulation 30:32 — Where supplements fit into the picture 31:18 — Magnesium, phosphatidylserine and adaptogens 33:08 — Why menopause requires a systems approach 34:15 — Practical steps to start making changes 35:38 — What to consider when HRT isn't working 36:25 — Why hormone dosing and delivery can vary between women 37:20 — Looking beyond a narrow hormone-only approach 37:51 — Final thoughts and what to explore next 👉 For more evidence-based conversations about perimenopause, menopause, hormones, brain health, sexual health, and the research shaping women's health, don't forget to subscribe! @drbettymurray 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelld
- 2 weeks ago25 min
The Grief No One Talks About: Menopause, Caregiving & the Weight We Carry
Menopause Mastery | The Grief No One Talks About: Menopause, Caregiving & the Weight We Carry | Ep. 296 solocast 🌿Welcome to The Menopause Mastery Show! What happens when you're the one everyone depends on—but you never get a chance to stop and feel what you're carrying? ❤️🩹 In this deeply personal episode of Menopause Mastery, Dr. Betty Murray talks about the grief that can surface in midlife: losing parents, caring for aging family members, losing a beloved pet, and mourning the dreams and parts of ourselves we had to put aside. This is the side of menopause and midlife that doesn't show up on a hormone panel—but it can profoundly affect how we feel, function, and move through everyday life. Dr. Murray shares her experience navigating her father's death, her mother's catastrophic stroke and nearly three years of caregiving, and the sudden loss of her dog, Bradley. She also explores disenfranchised grief, the emotional burden of the sandwich generation, and why grief doesn't necessarily disappear when we stay busy. Sometimes it simply changes shape. If you're caring for a parent, managing a household, building a career, navigating perimenopause or menopause, or quietly carrying a loss you haven't had time to process, this episode is a reminder: you don't have to wait for life to calm down before giving yourself permission to grieve. 🌱 00:00 — Why I'm Talking About Grief Today The original recording was lost, and the conversation returned at a time when grief was still very raw. 00:43 — Losing Bradley: When Grief Makes You Go Still A sudden loss and the unexpected physical and emotional response that followed. 001:51 — The Grief of Losing a Parent How the death of Dr. Betty Murray's father—and later her mother—changed her understanding of grief. 02:11 — The Part of Midlife No Hormone Panel Can Measure Caregiving, emotional weight, and why women often don't allow themselves to feel unwell. 04:06 — A Complicated Relationship With My Mom The complexity of grief when a parent-child relationship isn't simple. 05:06 — From Daughter to Caregiver Overnight The dramatic shift that followed her mother's heart attack and stroke. 05:56 — The Invisible Work of Caregiving Medical decisions, financial responsibilities, paperwork, business, patients, and finishing a PhD—all at once. 06:28 — Grieving Before Someone Is Gone How dementia and prolonged decline can create a form of grief long before death. 07:13 — The Sandwich Generation by the Numbers The scale of caregiving in the U.S. and the disproportionate burden carried by women. 08:32 — The Mental Load Is More Than Time Insurance, medications, phone calls, guilt, burnout, and the emotional responsibility of caregiving. 09:00 — Menopause + Caregiving + Everything Else Why the combination creates such a complex load for women in midlife. 10:17 — Why Losing a Pet Can Hurt So Much Why Bradley's death felt enormous—and why there was an instinct to minimize that grief. 10:40 — What Is Disenfranchised Grief? The experience of grieving a loss that society may not recognize as legitimate. 12:05 — What the Research Says About Pet Loss Research examining the intensity of grief following the loss of a pet. 13:14 — When the Clinical Framework Doesn't Match the Human Experience Why pet loss can be profoundly distressing even when traditional diagnostic frameworks don't recognize it in the same way. 14:24 — Your Nervous System Didn't Get the Memo A powerful reminder that grief doesn't become smaller just because someone tells you it should. 14:49 — Grieving Someone Who Is Still Alive The unique grief that can accompany dementia, decline, and watching someone change. 15:14 — The Dreams We Bury Along the Way Career goals, personal dreams, and other parts of life women may put aside while managing family responsibilities. 16:52 — The Grief That Never Gets a Funeral Why unfulfilled dreams and postponed parts of ourselves can resurface later. 17:16 — We Don't Skip Grief Because We Don't Feel It "We skip it because we don't have a slot for it." 18:00 — There Is Never a Convenient Time to Fall Apart The endless demands that make women postpone their own emotional needs. 18:34 — When Grief Changes Shape How unresolved grief can show up as exhaustion, irritability, emotional reactions, and feeling disconnected. 19:38 — I Don't Have This Mastered Either Choosing to name grief instead of simply narrating it privately. 20:24 — Scheduling Time to Fall Apart How slowing down and intentionally creating space helped make room for grief. 21:30 — Stop Treating Grief Like a Problem to Solve Accepting that grief is nonlinear and can ret
- 3 weeks ago45 min
Your Gut Is Talking to Your Hormones: The Menopause Microbiome Connection
The Menopause Mastery Show | Your Gut Is Talking to Your Hormones: The Menopause Microbiome Connection | Ep. 295 with Dr. Eddie Romo 🌿Welcome to The Menopause Mastery Show! 👉 What if your gut microbiome is influencing far more than digestion? In this episode of Menopause Mastery, Dr. Betty Murray sits down with microbiologist Dr. Eddie Romo, to explore the powerful connection between the gut microbiome, estrogen metabolism, menopause, inflammation, and brain health. Dr. Romo explains why the microbiome should be viewed as an active metabolic ecosystem—not simply a collection of "good" and "bad" bacteria. They discuss the estrobolome, the role gut bacteria play in estrogen recycling, and why changes in estrogen during perimenopause and menopause can also change the microbiome. The conversation also challenges the idea that probiotics are a universal solution. Dr. Romo explains why personalized, longitudinal microbiome testing may provide a much clearer picture than a single snapshot, and why factors like diet, sleep, exercise, stress, hormones, fiber, fermented foods, and polyphenols all matter. They also explore the emerging relationship between the gut and Alzheimer's risk, systemic inflammation, the blood-brain barrier, hormone replacement therapy, and women's health—and discuss the future of more personalized microbiome and hormone testing. ☑️ Your gut microbiome is an active part of your biology—not a passive collection of bacteria. Supporting a healthy, diverse gut ecosystem may be an important piece of protecting hormonal balance, metabolic health, and brain function throughout menopause and beyond! 🔗 To connect with Dr. Romo: https://www.instagram.com/dr.eddieromo https://www.phbio.ai/ 00:00:00 — Introduction: Menopause, Hormones & the Microbiome 00:01:27 — Dr. Eddie Romo's Journey Into Microbiology 00:03:27 — Your Microbiome Is More Than "Bacteria" 00:04:38 — The Gut-Brain Connection & Alzheimer's 00:06:40 — Alzheimer's Isn't Just a Disease of the Brain 00:08:07 — Why Brain Plaques May Not Tell the Whole Story 00:09:18 — Leaky Gut, Inflammation & Brain Health 00:10:28 — The Microbiome-Hormone Connection 00:12:14 — What Is the Estrobolome? 00:14:17 — Beta-Glucuronidase & Estrogen Recycling 00:15:27 — Why the Microbiome Changes During Menopause 00:18:03 — AI & The Future of Personalized Health 00:19:21 — Why Women's Health Research Matters 00:20:03 — Estrogen, Gut Lining & Microbial Diversity 00:22:18 — Inflammation Is Multifactorial 00:24:19 — Hormone Replacement Therapy & the Gut 00:26:42 — Could Hormone Therapy Affect Your Microbiome? 00:27:23 — Menopause, IBS & Digestive Symptoms 00:28:45 — Are Probiotics Overhyped? 00:30:42 — Why Your Microbiome Is Uniquely Yours 00:31:30 — Why Longitudinal Microbiome Testing Matters 00:32:18 — From Probiotics to Personalized Interventions 00:33:34 — Fiber, Fermented Foods & Polyphenols 00:35:01 — The Future of Microbiome Testing 00:36:39 — Your Microbiome Is Constantly Changing 00:37:29 — Toward Personalized Microbiome Recommendations 00:38:22 — Why Current Microbiome Testing Has Limitations 00:40:30 — Condition-Specific Microbiome Testing 00:42:05 — The Bigger Picture: Hormones + Gut + Systemic Health 00:43:18 — Where to Follow Dr. Romo & What's Coming Next 00:44:30 — What's Next for Menopause Mastery 00:45:10 — Closing & Listener Call to Action 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: 🔹The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ 🔹Menrva Telemedicine: https://gethormonesnow.com/ 🔹Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time. #menopausemastery #menopausepodcast #drbettymurray #menopause #perimenopause #postmenopause #andropause #womenshealth #hormonehealth #guthealth #microbiome #midlifehealth
- Sep 2, 202634 min
I Changed My Mind About GLP-1s: What You Need to Know About Ozempic, HRT, and Longevity
Menopause Mastery | I Changed My Mind About GLP-1s: What You Need to Know About Ozempic, HRT, and Longevity | Ep. 294 solocast with Dr. Betty Murray 🌿Welcome to The Menopause Mastery Show! 👉 What if midlife weight gain isn't a failure of willpower—but a biological shift that requires a different strategy? In this episode of Menopause Mastery, Dr. Betty Murray is making a confession: She's changed my mind about GLP-1 medications. When medications like semaglutide and tirzepatide first exploded into mainstream culture, she was deeply skeptical—not because she doubted the underlying science, but because she was concerned about inappropriate prescribing, aggressive dosing, inadequate monitoring, and the lack of guidance around nutrition, protein, resistance training, and hormones. Now, with more research and clinical experience available, the conversation has changed. We explore what GLP-1 medications may do beyond weight loss, including their relationship with inflammation, insulin sensitivity, cardiovascular health, and metabolic health—and why the midlife context matters. We also dig into the potential role of combining GLP-1 therapy with hormone replacement therapy, the concerns around muscle loss and inadequate protein intake, why some clinicians are exploring lower-dose approaches, and what women should consider measuring before making decisions about metabolic health. Most importantly, this episode is about precision rather than quick fixes. Your scale isn't the only measure of health. Muscle strength, body composition, bone density, metabolic markers, inflammation, hormones, and long-term health span all belong in the conversation. Topics covered: 🔹 Why I changed my perspective on GLP-1 medications 🔹 What happens metabolically during perimenopause and menopause 🔹 GLP-1s and inflammation 🔹 GLP-1s, cardiovascular and kidney health 🔹 GLP-1s and hormone replacement therapy 🔹 Protein and resistance training during GLP-1 therapy 🔹 Concerns around muscle loss and aggressive dosing 🔹 Lower-dose and "microdosing" approaches 🔹 DEXA scans and metabolic testing 🔹 Building a muscle-centric approach to midlife health 🔹 Looking beyond the bathroom scale toward longevity and health span As always, the goal of Menopause Mastery is to help you better understand the science, recognize where the evidence is strong or still emerging, and stay informed about the future of women's health. For more evidence-based conversations about perimenopause, menopause, hormones, brain health, sexual health, and the research shaping women's health, don't forget to subscribe! @drbettymurray 00:00 — I changed my mind about GLP-1s 02:00 — The problem with the "Wild West" of GLP-1 prescribing 04:00 — What actually changes in your body during midlife 06:30 — GLP-1s are more than weight-loss drugs 09:00 — Inflammation, cardiovascular health, and kidney protection 11:00 — GLP-1s + HRT: Why the combination matters 14:00 — The problem with pushing doses higher 17:00 — What is "microdosing"? 20:00 — My own experience with GLP-1 medication 22:30 — A real-world midlife patient example 25:00 — Build the metabolic foundation first 28:00 — Muscle-centric medicine for midlife women 30:00 — Hormones, GLP-1s, and longevity 32:00 — Three questions to rethink your midlife health 33:15 — Final thoughts: Own your midlife mastery 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time. 🌿 #menopausemastery #menopausepodcast #drbettymurray #menopause #perimenopause #postmenopause #andropause #womenshealth #menopauseresearch #midlifehealth #glp1
- Aug 26, 202631 min
6 New Menopause Studies Every Woman Should Know About
Menopause Mastery | 6 New Menopause Studies Every Woman Should Know About | Ep. 293 solocast with Dr. Betty Murray 🌿Welcome to The Menopause Mastery Show! In this episode, Dr. Betty Murray takes a closer look at six recent studies exploring some of the biggest unanswered questions in perimenopause and menopause research. From the surprising role of the postmenopausal ovary to the global factors associated with early menopause, new nonhormonal approaches to vaginal health, and the disconnect between what women experience and what gets documented in the doctor's office, these studies reveal just how much there is still to learn. Dr. Betty also explores why so many women don't recognize that they're in perimenopause, why symptoms like brain fog, fatigue, mood changes, and memory issues may appear long before hot flashes, and what emerging research on CBD and cognitive function could mean for future study. This episode covers: * New research into immune activity in postmenopausal ovaries * What a global study reveals about early menopause and socioeconomic factors * A potential nonhormonal approach to vaginal tissue health * The gap between menopause symptoms women discuss online and what clinicians document * Why 1 in 3 women may be uncertain about their reproductive stage * The neurological symptoms of perimenopause that may appear before hot flashes * Emerging research on CBD, estrogen, memory, and the endocannabinoid system * Why greater investment and attention in menopause research matters This episode is not about chasing headlines or making clinical promises. It's about looking at the research, understanding its limitations, and asking better questions about where menopause science is heading. 🌿 As always, the goal of Menopause Mastery is to help you better understand the science, recognize where the evidence is strong or still emerging, and stay informed about the future of women's health. For more evidence-based conversations about perimenopause, menopause, hormones, brain health, sexual health, and the research shaping women's health, don't forget to subscribe! @drbettymurray 00:00 6 New Menopause Studies 03:12 Are Postmenopausal Ovaries Still Active? 09:57 Early Menopause & Global Health 14:01 A New Nonhormonal Vaginal Treatment? 17:21 What Doctors Miss About Menopause 22:09 Why 1 in 3 Women Don't Know They're in Perimenopause 24:33 CBD, Estrogen & Memory 30:09 Why Menopause Research Matters 30:54 The Future of Women's Health 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH ✨ Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time. #menopausemastery #menopausepodcast #drbettymurray #menopause #perimenopause #postmenopause #andropause #womenshealth #menopauseresearch #midlifehealth
- Aug 19, 202651 min
Menopause and Genetics: Why Your DNA Test Might Be Missing the Real Story
Menopause Mastery | Menopause and Genetics: Why Your DNA Test Might Be Missing the Real Story | Ep. 292 with Dr. Tracey Steady-Hardcastle 🌿Welcome to The Menopause Mastery Show! In this episode, Dr. Betty Murray talks with Dr. Tracey Steady-Hardcastle of The DNA Company about how functional genomics can help women better understand the changes happening in perimenopause and menopause. They dig into why many common DNA tests feel overwhelming or too narrow, and why a polygenic approach can give a more useful picture of how genes work together. The conversation also covers estrogen detoxification myths, MTHFR, cardiovascular risk, mood, exercise recovery, and how genetics can support more personalized decisions around diet, lifestyle, nutrition, and supplementation. In this episode, you'll learn: 🔹Why single-gene testing often misses the bigger picture 🔹What polygenic scores are and why they matter 🔹How genetics can inform menopause support 🔹What MTHFR really does and why it gets oversimplified 🔹How genes may influence mood, recovery, detoxification, and cardiovascular risk 🔹How functional genomics can help personalize health decisions If you've ever looked at a genetic report and thought, "Okay, but what does this actually mean for me?", this episode is for you. 👉 About Dr. Tracey Steady-Hardcastle: Dr. Tracey Steady is an expert in functional genomics, acupuncture, and Chinese medicine with more than two decades of experience helping women navigate perimenopause and menopause. Connect with her at: https://thednacompany.com/ 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH Thank you for listening to Menopause Mastery. Empowering your health journey, one episode at a time. #menopausemastery #menopausepodcast #drbettymurray #menopause #perimenopause #postmenopause #andropause #womenshealth #dna #menopausegenetics #genetics Menopause Mastery — Show Note Chapters 00:00 — Why Menopause Can Make Your Body Feel Completely Different 02:24 — Dr. Tracey Steady's Path Into Functional Genomics 04:23 — Why Single-Gene Testing Can Miss the Bigger Picture 05:16 — Methylation, MTHFR, and the Problem With One-Gene Solutions 08:03 — DIM, Estrogen Metabolism, and Over-Supplementation 09:17 — Genetic Disease vs. Functional Genomics 13:32 — Using Genetics to Make Smarter Health Decisions 16:20 — Carbs, Saturated Fat, and Personalized Nutrition 17:25 — Why Keto May Not Work for Everyone 20:53 — Genetics Helps You Ask Better Health Questions 22:05 — Hormones, Neurotransmitters, and Polygenic Scoring 23:27 — COMT, Estrogen Fluctuations, and Perimenopausal Mood 26:15 — The "Slow COMT" Personality and Stress Response 29:59 — How Genetics Can Point to Better Testing 34:10 — Genetics and Hormone Production, Binding, and Metabolism 35:57 — What "Estrogen Toxicity" Really Means 37:13 — Detoxification Pathways, the Gut, and Hormone Elimination 39:56 — Why Women's Health Can't Be Treated in Silos 41:25 — Genetics, Exercise Performance, and Recovery 44:16 — How Genetics May Affect Hormone Therapy Response 45:58 — DNA 180 vs. the Newer DNA Testing Panel 48:29 — Prioritizing Your Biggest Health Risks and Opportunities 51:04 — Final Takeaways and Where to Learn More
- Aug 12, 202634 min
Beyond Hormones: The Cellular Health Secrets to Aging Wel
Menopause Mastery| Beyond Hormones: The Cellular Health Secrets to Aging Well | Episode 291 🌿Welcome to The Menopause Mastery Show! What if the fatigue, brain fog, and changes you experience during perimenopause and menopause aren't just about hormones? 🤔 In this episode of Menopause Mastery, Dr. William Haas, MD, MBA, joins Dr. Betty Murray for a fascinating conversation about the often-overlooked foundation beneath hormone health: cellular health and mitochondrial energy production. Dr. Haas shares his journey from family medicine and human performance into root-cause and cellular health medicine, including his own experience with energy, fatigue, and brain fog in his 40s. We explore how mitochondria, oxidative stress, nutrition, sleep, circadian rhythm, exercise, and hormones all interact—and why simply adding hormones or supplements may not address the underlying problem. We also dive into the rapidly evolving world of biohacking, including IV nutrient therapy, ozone, hyperbaric oxygen, peptides, exosomes, and stem cells. Dr. Haas explains why foundational health needs to come first and why his philosophy is to "recharge before you repair" and "detox before you redox." In this episode: * Menopause symptoms shouldn't automatically be viewed as a hormone problem alone. * Mitochondria play a central role in producing the cellular energy needed for repair and normal function. * Dr. Haas recommends looking for patterns in symptoms and testing rather than simply prescribing a collection of supplements. * Sleep consistency and morning light are foundational tools for supporting circadian and mitochondrial function. * IV nutrient therapy may have a role when nutrient absorption or deficiencies are significant. * Advanced therapies such as ozone and hyperbaric oxygen require thoughtful dosing and appropriate clinical guidance. * Peptides should be approached with particular attention to evidence, sourcing, dosing, and medical supervision. * Hormones and cellular health should be considered together rather than as completely separate systems. * Protein before coffee and appropriately used creatine are among Dr. Haas's practical strategies for supporting energy metabolism. * Intermittent fasting can become counterproductive when it turns into chronic under-eating. * VO2 max can serve as a useful benchmark when tracking fitness, metabolic health, and health span over time. * The overarching philosophy: "recharge before you repair." Finally, Dr. Haas shares practical strategies women can consider for supporting cellular energy, including protein before coffee, creatine, avoiding poorly implemented intermittent fasting, and using VO2 max as a powerful marker of health span and longevity. 👉 If you've been told your symptoms are normal, or you've tried hormone support and still don't feel like yourself, this conversation offers a broader way to think about healing. Don't forget to share with someone who needs a more complete conversation about menopause, energy, and cellular health. 00:00 — Introduction and The Importance of Cellular Health with Guest Dr. William Haas 02:05 — Dr. Haas's Journey Into Root-Cause Medicine 04:25 — Why Menopause Isn't Just About Hormones 06:15 — What Is Cellular Health? 08:25 — How to Recognize Mitochondrial Stress 10:35 — Micronutrients, Oxidative Stress & Testing 13:00 — Why Oxidative Stress Matters During Menopause 15:05 — The Foundations of Cellular Health 17:10 — Biohacking: IV Therapy, Ozone & HBOT 20:15 — Gut Health & Nutrient Absorption 22:15 — Ozone & Hyperbaric Oxygen Therapy 24:15 — Integrating Hormones With Cellular Health 26:15 — Peptides: Potential, Safety & the Gray Market 29:05 — The "Recharge Before Repair" Approach 30:25 — Practical Strategies: Protein, Creatine & Intermittent Fasting 32:15 — VO2 Max, Metabolic Health & Longevity 33:45 — Where to Find Dr. William Haas 34:30 — Final Thoughts Connect with Dr. Haas: Website: https://vyvewellness.com 📌 Connect with Dr. Betty Murray: Website: https://www.drbettymurray.com/ Instagram: https://www.instagram.com/drbettymurray/ ✅ Let us know what you think! Like, comment, and subscribe on YouTube: @drbettymurray 🔗 Links: The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/ Menrva Telemedicine: https://gethormonesnow.com/ Living Well Dallas: https://www.livingwelldallas.com/ 🎙️ More from the Podcast: Subscribe to #MenopauseMastery → https://www.youtube.com/channel/UCwONPdSvb2-YYY74VhD-XBw Apple Podcasts → https://podcasts.apple.com/us/podcast/menopause-mastery/id1607369247 Spotify → https://open.spotify.com/show/0tNsjm32CZNXSgSFEwS3uH Than
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About Menopause Mastery
Welcome to Menopause Mastery with Dr. Betty Murray. This show is for women in the second season of life, the season of menopause, who are ready for more: health - vitality - passion - and purpose! Join host, Dr. Betty Murray (part geek, part magician, and your new medical bestie with a dash of sass), as she takes complex science and makes it easier to integrate into daily life. Nutrition, hormones, functional medicine, and a wellness lifestyle are only the tip of the conversation. Join the journey to uncover your deepest desires, harness your physical and mental health, and peel back the layers to know exactly what you want out of life.
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